774242-01-2

Upstream product

• 127451-46-1 N-(4-acetoxybut-2-enyl)-N-(prop-2-ynyl)-p-toluenesulfonamide 
• 55022-46-3 4-methyl-N-prop-2-ynylbenzenesulfonamide 
• 774241-78-0 N-((2Z)-4-{[tert-butyl(dimethyl)silyl]oxy}but-2-en-1-yl)-4-methyl-N-prop-2-yn-1-ylbenzenesulfonamide 

Downstream Products

• 1334209-45-8 (E)-6-(N-(prop-2-ynyl)-N-tosylamino)hex-4-en-1-yn-3-yl pivalate 
• 1334209-47-0 (E)-6-(N-(3-phenylprop-2-ynyl)-N-tosylamino)hex-4-en-1-yn-3-yl pivalate 
• 1365555-72-1 C₂₂H₂₁NO₃S 
• 1365555-08-3 (E)-ethyl 7-(N-(prop-2-ynyl)-N-tosylamino)-4-(pivaloyloxy)hept-5-en-2-ynoate 
• 1365555-10-7 (E)-1-(N-(prop-2-ynyl)-N-tosylamino)-7-oxooct-2-en-5-yn-4-yl pivalate 
• 1365555-11-8 (E)-1-(N-(prop-2-ynyl)-N-tosylamino)-7-oxododec-2-en-5-yn-4-yl pivalate 
• 1365555-62-9 C₁₉H₂₁NO₅S 
• 1365555-13-0 (E)-7-(N-(prop-2-ynyl)-N-tosylamino)-1-oxo-1-phenylhept-5-en-2-yn-4-yl pivalate 
• 1365555-64-1 C₂₉H₄₃NO₅SSi 
• 1365555-22-1 (E)-6-(N-(3-phenylprop-2-ynyl)-N-tosylamino)-1-bromohex-4-en-1-yn-3-yl pivalate 
• 384836-87-7 (2E)-N-(3-formyl-2-propenyl)-N-(2-propynyl)tosylamide 
• 1372714-32-3 C₁₄H₁₇NO₃S 

Relevant academic research and scientific papers

Rhodium-catalyzed intra- and intermolecular [5 + 2] cycloaddition of 3-acyloxy-1,4-enyne and alkyne with concomitant 1,2-acyloxy migration

A new type of rhodium-catalyzed [5 + 2] cycloaddition was developed for the synthesis of seven-membered rings with diverse functionalities. The ring formation was accompanied by a 1,2-acyloxy migration event. The five- and two-carbon components of the cycloaddition are 3-acyloxy-1,4-enynes (ACEs) and alkynes, respectively. Cationic rhodium(I) catalysts worked most efficiently for the intramolecular cycloaddition, while only neutral rhodium(I) complexes could facilitate the intermolecular reaction. In both cases, electron-poor phosphite or phosphine ligands often improved the efficiency of the cycloadditions. The scope of ACEs and alkynes was investigated in both the intra- and intermolecular reactions. The resulting seven-membered-ring products have three double bonds that could be selectively functionalized.

Diastereoselective intramolecular temporary silicon-tethered rhodium-catalyzed [4+2+2] cycloisomerization reactions: Regiospecific incorporation of substituted 1,3-butadienes

Transition metal-catalyzed carbocyclization reactions represent powerful methods for the construction of complex polycyclic systems. We have developed a regiospecific and diastereoselective intramolecular temporary silicon-tethered rhodium-catalyzed [4+2+