77445-88-6Relevant academic research and scientific papers
Indole fluorescence probe as well as preparation method and application thereof
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Paragraph 0050-0051; 0058-0062, (2020/03/17)
The invention belongs to the technical field of biological medicine, and particularly relates to an indole fluorescence probe and a preparation method and application. thereof, and provides an indole fluorescence probe, of formula I as shown, in the formu
Evaluation of novel N 1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands
Pike, Victor W.,Taliani, Sabrina,Lohith, Talakad G.,Owen, David R. J.,Pugliesi, Isabella,Da Pozzo, Eleonora,Hong, Jinsoo,Zoghbi, Sami S.,Gunn, Roger N.,Parker, Christine A.,Rabiner, Eugenii A.,Fujita, Masahiro,Innis, Robert B.,Martini, Claudia,Da Settimo, Federico
experimental part, p. 366 - 373 (2011/03/18)
A novel series of N1-methyl-(2-phenylindol-3-yl)glyoxylamides, 19-31, designed in accordance with our previously reported pharmacophore/ topological model, showed high affinity for the 18 kDa translocator protein (TSPO) and paved the way for de
N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Renzodiazepine Receptor
Primofiore, Giampaolo,Da Settimo, Federico,Taliani, Sabrina,Simorini, Francesca,Patrizi, Maria Paola,Novellino, Ettore,Greco, Giovanni,Abignente, Enrico,Costa, Barbara,Chelli, Beatrice,Martini, Claudia
, p. 1852 - 1855 (2007/10/03)
We report the synthesis and the affinity data at both the peripheral (PBR) and the central benzodiazepine receptors of a series of N,N-dialkyl-2-phenylindol-3-ylglyoxylamide derivatives III, designed as conformationally constrained analogues of 2-phenylin
