77455-64-2Relevant academic research and scientific papers
3-QUINOLINE-2-(1H)-YLIDENEINDOLIN-2-ONE DERIVATIVES
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Page 25, (2010/02/05)
There is provided medicaments, particularly a vascular endothelial growth factor (VEGF) inhibitor which is useful as a therapeutic drug for solid tumors, diabetic retinopathy and the like diseases in which angiogenesis is taking a role. That is, since a novel 3-quinolin-2(1H)-ylideneindolin-2-one derivative or a salt thereof has good VEGF inhibitory action, angiogenesis inhibitory action and anti-tumor action, it is useful as ideal VEGF inhibitor, angiogenesis inhibitor and anti-tumor agent.
Comparative Reactivity of Substituted 4-Nitrobenzylidene Dichlorides with Alkali
Goh, Swee Hock,Kam, Toh Seok
, p. 423 - 426 (2007/10/02)
A comparative study of the reactions of substituted 4-nitrobenzylidene dichlorides ArCHCl2 (Ar = 3-Cl-4-NO2C6H3, 2-Cl-4-NO2C6H3, 4-NO2C6H4, 3,5-Me2-4-NO2C6H2, and 2-Me-4-NO2C6H3) with aqueous alcoholic alkali shows that chlorine substitution enhances the
