774582-60-4

Usage

Class

Organic compounds, phenylimidazoles

Structure

Imidazole ring with a phenyl group substitution

Substitution positions

6-bromo, 2-methyl, 4-phenylmethoxy

Potential pharmacological properties

Antiviral, antimicrobial, anticancer

Applications

Pharmaceutical research and drug development, organic synthesis, material science.

Upstream product

• 100-39-0 benzyl bromide 
• 713530-47-3 2-(benzyloxy)-4-bromo-6-nitrobenzenamine 
• 942195-80-4 N-[4-bromo-2-nitro-6-(benzyloxy)phenyl]acetamide 
• 89521-54-0 2-(benzyloxy)-6-nitroaniline 
• 100-44-7 benzyl chloride 
• 603-85-0 2-Amino-3-nitrophenol 

Downstream Products

• 774582-80-8 4-(benzyloxy)-6-bromo-2-methyl-1-{[2-(trimethylsilyl)ethoxy]-methyl}-1H-benzimidazole 
• 942195-88-2 6-bromo-2-methyl-1-[(4-methylphenyl)sulfonyl]-4-[(phenylmethyl)oxy]-1H-benzimidazole 
• 774582-59-1 4-benzyloxy-6-bromo-1-methoxymethyl-2-methyl-1H-benzimidazole 
• 942195-86-0 4-hydroxy-N N,2-trimethyl-1-[(4-methylphenyl)sulfonyl]-1H-benzimidazole-6-carboxamide 
• 942195-85-9 N,N,2-trimethyl-1-[(4-methylphenyl)sulfonyl]-4-[(phenylmethyl)oxyl]-1H-benzimidazole-6-carboxamide 
• 1015174-89-6 5-[(dimethylamino)methyl]-4-hydroxy-N,N,2-trimethyl-1-[(4-methylphenyl)sulfonyl]-1H-benzimidazole-6-carboxamide 
• 1062272-07-4 N,N,2-trimethyl-3-[(4-methylphenyl)sulfonyl]-2',3',6,7-tetrahydro-3H-spiro[chromeno[7,8-d]imidazole-8,1'-indene]-5-carboxamide 
• 774582-77-3 7-hydroxy-2-methyl-6-(3-oxo-3-phenyl-propyl)-3-(2-trimethylsilanyl-ethoxymethyl)-3H-benzoimidazole-5-carboxylic acid dimethylamide 
• 911048-67-4 (8S)-2-methyl-8-phenyl-3-(2-trimethylsilanyl-ethoxymethyl)-3,6,7,8-tetrahydro-chromeno[7,8-d]imidazole-5-carboxylic acid dimethylamide 
• 911048-69-6 (8S)-2-methyl-8-phenyl-3,6,7,8-tetrahydro-chromeno[7,8-d]imidazole-5-carboxylic acid dimethylamide oxalyc acid salt 

Relevant academic research and scientific papers

Synthesis method of agaronoprazan

The method comprises the following steps: preparing 4 - hydroxyl - N, N, 2 - trimethyl - 1H - benzimidazole -6 - formamide. Preparation of (S)-5, 7 - difluoro -3, 4 - dihydro - 2H - chromene -4 - alcohol, and last photoreaction: Mitsunobu ((s)-4 - ((5, 7

BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS

Abstract This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R4, A and E are each as described herein or a pharmaceutically acceptable salt

SPIRO BENZIMIDAZOLE DERIVATIVES AS ACID PUMP INHIBITORS

This invention relates to compounds of the formula (I): (I) or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R4, R5, R6, R7, R8 and A are each as described herein or a pharmaceutically acceptable salt, and compositions containing such c

Chromane Substituted Benzimidazole Derivatives

This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5, R6, R7 and R8 are each as

7-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION

The invention provides compounds of the formula (1), in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.