77461-99-5Relevant academic research and scientific papers
Synthesis of rac-ɑ-aryl propionaldehydes via branched-selective hydroformylation of terminal arylalkenes using water-soluble Rh-PNP catalyst
Chen, Fen-Er,Gao, Peng,Ke, Miaolin,Liang, Guanfeng,Ru, Tong
, (2021/08/26)
This work detailed the preparation of a class of water-soluble PNP ligands that differed by the nature of the substitute on phenyl ring of ligands. These ligands were incorporated into water-soluble rhodium-PNP complex catalysts that were used to regioselective hydroformylation of a series of terminal arylalkenes, providing efficient access to rac-α-aryl propionaldehydes in good to excellent yield (up to 97%) and branched-regioselectivity (up to 40:1 b/l ratio). Furthermore, gram-scale and diverse synthetic transformation demonstrated synthetic application of this methodology for non-steroidal antiinflammatory drugs.
Synthesis of Functional Chelating Diphosphines Containing the Bisamino Moiety and the Use of These Materials in the Preparation of Water-Soluble Diphosphine Complexes of Transition Metals
Nuzzo, Ralph G.,Haynie, Sharon L.,Wilson, Michael E.,Whitesides, George M.
, p. 2861 - 2867 (2007/10/02)
Acylation of bisamine provides a flexible synthesis of functionalized chelating diphosphines.This reaction offers a route to diphosphine complexes of transition metals having a wide range of structures and physical properties and especially to water-soluble complexes.The aqueous solubility of the free ligands and of the complexes prepared from them depend on the ligand, on the metal, and on other materials (especially surfactants) present in the solution.We describe typical preparations of ligands and outline the properties of their complexes with certain transition metals.
