77495-40-0 Usage
Uses
Used in Pharmaceutical Industry:
Aminophenazone is utilized as an analgesic for the treatment of minor aches and pains, as well as an antipyretic to reduce fever. Its ability to inhibit prostaglandin production makes it effective in managing inflammation and fever associated with various conditions.
Used in Over-the-Counter Medications:
Aminophenazone is found in over-the-counter pain relief medications, providing quick relief from mild to moderate pain and fever. Its accessibility and effectiveness make it a popular choice for self-medication.
Used in Topical Medications:
In addition to oral administration, aminophenazone can be applied topically in the form of creams or gels. This allows for localized treatment of pain and inflammation, offering an alternative to oral medications for certain conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 77495-40-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,4,9 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77495-40:
(7*7)+(6*7)+(5*4)+(4*9)+(3*5)+(2*4)+(1*0)=170
170 % 10 = 0
So 77495-40-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2O4/c1-6(14)13-9-5-10(16-2)7(4-8(9)12)11(15)17-3/h4-5H,12H2,1-3H3,(H,13,14)
77495-40-0Relevant academic research and scientific papers
A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with dual antiemetic and gastroprokinetic activities
Hirokawa, Yoshimi,Yamazaki, Hiroshi,Yoshida, Naoyuki,Kato, Shiro
, p. 1973 - 1978 (2007/10/03)
A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with a medium perhydroazacycle ring in the amine moiety were prepared, and their antiemetic and gastroprokinetic activities were evaluated. Among them, N-(1-ethylhexahydroazepin-3-yl)-, N-(1-ethyloctahydroazocin-3-yl)- and N-(1- ethyloctahydroazonin-3-yl)-6-methoxy-1H-benzotriazole-5-carboxamides (24, 36, 37) showed a potent antiemetic activity (inhibition of apomorphine-induced emesis in dogs) along with gastroprokinetic activity (gastric emptying in rats).
