59338-92-0

Usage

Uses

Used in Aerospace and Automotive Industries:
MBCA is used as a corrosion inhibitor for protecting metal surfaces from corrosion by forming a protective film. This application is particularly important in the aerospace and automotive industries, where metal components are exposed to harsh environments and need to maintain their integrity and performance.
Used in Plastics Industry:
MBCA is used as a stabilizer for plastics, enhancing their durability and resistance to degradation. This helps in extending the lifespan of plastic products and maintaining their quality.
Used in Coatings Industry:
MBCA is used as a UV absorber in coatings, providing protection against harmful ultraviolet radiation. This is particularly useful in outdoor coatings, where exposure to sunlight can cause degradation and fading of the coating.
Used in Organic Synthesis:
MBCA is used as a reagent in organic synthesis, enabling the production of various chemical compounds. Its unique structure and properties make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.

InChI:InChI=1/C8H7N3O3/c1-14-7-3-6-5(9-11-10-6)2-4(7)8(12)13/h2-3H,1H3,(H,12,13)(H,9,10,11)

Upstream product

• 59338-93-1 alizapride 
• 4093-41-8 methyl 4-acetamido-2-methoxy-5-nitrobenzoate 
• 4093-29-2 methyl 4-(acetylamino)-o-anisate 
• 77495-40-0 methyl 4-(acetylamino)-5-amino-o-anisate 
• 59338-89-5 1-Acetyl-6-methoxy-1H-benzotriazole-5-carboxylic acid methyl ester 

Downstream Products

• 59338-86-2 6-methoxy-1H-benzotriazole-5-carboxylic acid methyl ester 

Relevant academic research and scientific papers

A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with dual antiemetic and gastroprokinetic activities

A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with a medium perhydroazacycle ring in the amine moiety were prepared, and their antiemetic and gastroprokinetic activities were evaluated. Among them, N-(1-ethylhexahydroazepin-3-yl)-, N-(1-ethyloctahydroazocin-3-yl)- and N-(1- ethyloctahydroazonin-3-yl)-6-methoxy-1H-benzotriazole-5-carboxamides (24, 36, 37) showed a potent antiemetic activity (inhibition of apomorphine-induced emesis in dogs) along with gastroprokinetic activity (gastric emptying in rats).

Method for enhancing memory or correcting memory deficiency with arylamidopyrazolidines and arylamidodiazabicycloalkanes

A pharmaceutical method for improving memory or correcting memory deficiency is disclosed, utilizing compounds having the formula: STR1 wherein m and n are zero and one and when m is zero, the dotted line represents a double bond; X is oxygen or sulfur; R1 and R2 are hydrogen, loweralkyl, phenyl or phenylloweralkyl, or R1 and R2 taken together may form a fused second ring with the nitrogen atoms having three or four methylene groups to which may be attached at any second ring carbon atom thereof, a loweralkyl or phenyl radical; R3 is hydrogen or loweralkyl; Ar is phenyl, pyridyl, furanyl, thienyl, methoxy-1H-benzotriazolyl, indolinyl, methoxyindolinyl, methoxypyrimidinyl, aminomethoxypyrimidinyl, 1,3-benzodioxolyl or naphthalenyl, the active optical isomers; and the pharmaceutically acceptable acid addition salts thereof.

Hydrolysis of the antiemetic drug alizapride

First order rate constants of the hydrolysis of N-[(1-allyl-2-pyrrolidinyl)-methyl]-6-methoxy-1H-benzotriazole-5-carboxami de (alizapride, Vergentan) in acid and alkaline medium were determined. The activation energy observed in alkaline solution was 60.3 kJ.mol-1. The substance was not hydrolized in vitro by esterase, liver homogenate or plasma.