775-10-0Relevant academic research and scientific papers
Non-Diazo C?H Insertion Approach to Cyclobutanones through Oxidative Gold Catalysis
Zheng, Zhitong,Wang, Youliang,Ma, Xu,Li, Yuxue,Zhang, Liming
, p. 17398 - 17402 (2020/08/14)
Cyclobutanones are synthetically versatile compounds that often require extensive effort to access. Herein, we report a facile synthesis of cyclobutanones based on the C(sp3)?H insertion chemistry of oxidatively generated gold carbenes. Various cyclobutanones were obtained in synthetically useful yields from substrates with minimal structural prefunctionalization. This discovery reveals new synthetic utilities of gold-catalyzed oxidative transformations of alkynones.
Metal- and Reagent-Free Intramolecular Oxidative Amination of Tri- and Tetrasubstituted Alkenes
Xiong, Peng,Xu, He-Huan,Xu, Hai-Chao
supporting information, p. 2956 - 2959 (2017/03/11)
A metal- and reagent-free, electrochemical intramolecular oxidative amination reaction of tri- and tetrasubstituted alkenes has been developed. The electrosynthetic method proceeds through radical cyclization to form the key C-N bond, allowing a variety of hindered tri- and tetrasubstituted olefins to participate in the amination reaction. The result is the efficient synthesis of a host of alkene-bearing cyclic carbamates and ureas and lactams.
Iron-mediated electrochemical reaction of α-chloroesters with carbonyl compounds
Durandetti, Muriel,Meignein, Clothilde,Perichon, Jacques
, p. 317 - 320 (2007/10/03)
(Matrix presented) Reformatsky-type reactions have been performed efficiently using an electroassisted iron-complex catalysis. Valuable product such as β-hydroxyesters, ketones or nitriles are thus prepared with high yields.
REACTIONS OF POLYHALOGENATED FUNCTIONAL COMPOUNDS WITH METALS AND ELECTROPHILIC REAGENTS. XIV. REACTION OF 2,2-DIHALOGENOPINACOLINES WITH ZINC AND CARBONYL COMPOUNDS
Shchepin, V. V.,Russkikh, N. Yu.,Gladkova, G. E.
, p. 1628 - 1631 (2007/10/02)
A new method was developed for the production of the E forms of α,β-unsaturated ketones on the basis of the reaction of 2,2-dibromo- and 2,2-dichloropinacolines, zinc, and carbonyl compounds.
MIXED KETONE-KETONE CONDENSATIONS UNDER THE CONDITIONS OF THE GRIGNARD-COLONGE METHOD
Sosnovskikh, V. Ya.,Esafov, V. I.,Andreev, N. S.
, p. 2096 - 2100 (2007/10/02)
The mixed condensation of aliphatic and aromatic methyl ketones was realized under the conditions of the Grignard-Colonge method.By dehydration of the synthesized β-ketols the β-methyl-α,β-unsaturated ketones with a sterically hindered carbonyl group were obtained.
