30263-65-1

Usage

Uses

Used in Organic Synthesis:
1,1-Dibromopinacolone is used as a reagent in organic synthesis for the preparation of complex organic molecules. Its high reactivity allows it to be a key component in creating intricate molecular structures.
Used in Pharmaceutical Production:
1,1-Dibromopinacolone serves as an intermediate in the production of pharmaceuticals. Its unique properties contribute to the synthesis of various medicinal compounds, enhancing the development of new drugs.
Used in Agrochemical Production:
In the agrochemical industry, 1,1-Dibromopinacolone is utilized as an intermediate for the synthesis of agrochemicals. Its role in creating effective compounds for agricultural applications is significant.
Safety Precautions:
Due to the potential reactivity and toxicity of 1,1-Dibromopinacolone, it should be handled with care and under appropriate safety measures to ensure the protection of both individuals and the environment.

InChI:InChI=1/C6H10Br2O/c1-6(2,3)4(9)5(7)8/h5H,1-3H3

Upstream product

• 75-97-8 3,3-dimethyl-butan-2-one 
• 7789-69-7 phosphorus pentabromide 

Downstream Products

• 4026-20-4 2-hydroxy-3,3-dimethylbutanoic acid 
• 41564-62-9 (E)-1-(4-chlorophenyl)-4,4-dimethylpent-1-en-3-one 
• 140427-72-1 (E)-1-(4-ethoxyphenyl)-4,4-dimethylpent-1-en-3-one 
• 22146-57-2 (2R)-3,3-Dimethyl-2-hydroxybutyric acid 
• 21641-92-9 (S)-2-hydroxy-3,3-dimethylbutanoic acid 
• 937-02-0 3-Amino-5-t-butyl-1,2,4-triazine 
• 5469-26-1 1-Bromopinacolon 
• 98991-64-1 ((C₆H₅)3P)2BrPdCHBrCOC₄H₉ 
• 99094-65-2 ((C₆H₅)3P)2BrPdCHBrCOC₄H₉ 
• 1240493-85-9 1-(4-chlorophenyl)-6,6-dimethyl-2-(2,2-dimethylpropanoyl)-5,7-dioxaspiro[2.5]octane-4,8-dione 
• 1240493-86-0 1-(4-bromophenyl)-6,6-dimethyl-2-(2,2-dimethylpropanoyl)-5,7-dioxaspiro[2.5]octane-4,8-dione 
• 1240493-88-2 2-(2,2-dimethylpropanoyl)-3-(4-fluorophenyl)spiro[cyclopropane-1,2'-indan]-1',3'-dione 
• 1240493-87-1 2-(2,2-dimethylpropanoyl)-3-phenylspiro[cyclopropane-1,2'-indan]-1',3'-dione 
• 775-10-0 1-cyclohexylidene-3,3-dimethyl-butan-2-one 

Relevant academic research and scientific papers

TMS·OTf-Catalyzed α-bromination of carbonyl compounds by N-bromosuccinimide

Various carbonyl compounds undergo α-bromination reaction under a mild and practical condition utilizing N-bromosuccinimide (NBS), catalyzed by trimethylsilyl trifluoromethanesulfonate (TMS·OTf). This method is also effective for the side-chain bromination of heteroaromatic carbonyl compounds without the ring brominations.

Asymmetric hydrogenation of tert-alkyl ketones

A combined system of RuCl2(tolbinap)(pica) and an alkaline or organic phosphazene base catalyzes asymmetric hydrogenation of sterically congested tert-alkyl ketones (TolBINAP = 2,2-bis(di-4-tolylphosphino)-1,1-binaphthyl, PICA = α-picolylamine). Hydrogenation with RuH(η1-BH4)(tolbinap)(pica) does not require any strong base. Alcoholic solvents strongly affect the catalytic efficiency. The reaction proceeds smoothly in ethanol under 1-20 atm of H2 and at room temperature with a substrate to catalyst molar ratio of up to 100000. Various aliphatic, aromatic, heteroaromatic, and olefinic tert-alkyl ketones are convertible to the corresponding chiral carbinols in high enantiomeric purity. Olefinic and heteroaromatic functions are left intact. Certain cyclic ketones are also usable. The mode of enantioface selection is consistent and predictable. Copyright