77517-29-4 Usage
Uses
Dihydromevinolin is used as an impurity in the production of Lovastatin bulk drug. It is important to monitor and control the levels of this impurity to ensure the safety and efficacy of the final product. The presence of dihydromevinolin can affect the quality and performance of Lovastatin, so it is crucial to minimize its concentration during the manufacturing process.
Check Digit Verification of cas no
The CAS Registry Mumber 77517-29-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,5,1 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77517-29:
(7*7)+(6*7)+(5*5)+(4*1)+(3*7)+(2*2)+(1*9)=154
154 % 10 = 4
So 77517-29-4 is a valid CAS Registry Number.
InChI:InChI=1/C24H38O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,14-21,23,25H,5,8-13H2,1-4H3/t14-,15-,16-,17-,18+,19+,20-,21-,23+/m0/s1
77517-29-4Relevant articles and documents
Total Synthesis of (+)-Dihydromevinolin
Hecker, Scott J.,Heathcock, Clayton H.
, p. 4586 - 4594 (2007/10/02)
A total syntheses of (+)-dihydromevinolin (2b) is presented, as well as the preparation of three analogues (62, 63, and 64) for assessment of their biological activity.Base-promoted fragmentation of the tosylhydrazone (20) of key intermediate 6 affords ac
Reductive Transformation and Cyclopropanation of Mevinolin (α-Methylcompactin). Generation of Chirality in the 1,4-Hydrostannation of a Cyclic Diene
Kuo, C. H.,Patchett, A. A.,Wendler, N. L.
, p. 1991 - 1998 (2007/10/02)
Conversion of mevinolin by direct reductive procedures as well as by indirect chemical transformations has permitted the preparation of the various di- and tetrahydro derivatives.Cyclopropanation of mevinolin and its derivatives has furnished mono- and di
