775287-75-7

Upstream product

• 874-63-5 3,5-dimethylmethoxybenzene 
• 1191240-42-2 2-(cyclopropylamino)ethanol hydrobromide 
• 55661-08-0 4-methoxy-2,6-dimethylbenzenesulfonyl chloride 
• 35265-06-6 2-(cyclopropylamino)ethan-1-ol 

Downstream Products

• 775287-76-8 [2-[cyclopropyl[(4-methoxy-2,6-dimethylphenyl)sulphonyl]amino]ethoxy]acetic acid,1,1-dimethylethyl ester 
• 1224586-78-0 N-(2-(2-chloropyrimidin-4-yloxy)ethyl)-N-cyclopropyl-4-methoxy-2,6-dimethylphenylsulfonamide 
• 1224586-77-9 N-(2-(4-chloropyrimidin-2-yloxy)ethyl)-N-cyclopropyl-4-methoxy-2,6-dimethylphenylsulfonamide 
• 1224584-11-5 N-cyclopropyl-4-methoxy-2,6-dimethyl-N-(2-(6-(9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yloxy)ethyl)benzenesulfonamide 
• 1186240-84-5 N-((1-(2-(2-(N-cyclopropyl-4-methoxy-2,6-dimethylphenylsulfonamido)ethoxy)acetyl)-4-(4-(pyridin-4-yl)piperazin-1-yl)piperidin-4-yl)methyl)acetamide 
• 1186240-82-3 N-((1-(2-(2-(N-cyclopropyl-4-methoxy-2,6-dimethylphenylsulfonamido)ethoxy)acetyl)-4-(4-cyclopropylpiperazin-1-yl)piperidin-4-yl)methyl)isonicotinamide 
• 1186240-80-1 N-cyclopropyl-N-(2-(2-(4-(4-cyclopropylpiperazin-1-yl)-4-((1-oxoisoindolin-2-yl)methyl)piperidin-1-yl)-2-oxoethoxy)ethyl)-4-methoxy-2,6-dimethylbenzenesulfonamide 

Relevant academic research and scientific papers

Substituted Spiroamine Compounds

Substituted spiroamine compounds corresponding to the formula (I) In which m, n, o, p, Q, r, s, t, R1, R2, R3, R4a, R4b, R5a, R5b, R6a, R6b, R7, R8, R9, R10 and R11 have defined meanings; a process for the preparation of such compounds, pharmaceutical compositions containing such compounds and the use of substituted spiroamines for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin 1 receptor.

Substituted Pyrimidine and Triazine Compounds

Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.

SUBSTITUTED SULFONAMIDE COMPOUNDS

Substituted sulfonamide compounds corresponding to formula I processes for the preparation thereof, pharmaceutical compositions containing these compounds, and the use of such substituted sulfonamide compounds in pharmaceutical compositions for the treatment and/or inhibition of pain and other conditions at least partly mediated by the bradykinin 1 receptor

SUBSTITUTED SULFONAMIDE DERIVATIVES

The invention relates to substituted sulfonamide derivatives, processes for the preparation thereof, medicaments containing these compounds and the use of substituted sulfonamide derivatives for the preparation of medicaments.

Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain

The present invention concerns novel benzenesulphonamide compounds, defined by formula I and the description, their method of preparation and their use in therapy.