775343-47-0Relevant academic research and scientific papers
Design, Synthesis, and Biological Evaluation of Imidazopyrazinone Derivatives as Antagonists of Inhibitor of Apoptosis Proteins (IAPs)
Kim, Jisook,Bae, Inhwan,Song, Jiyoung,Kim, Younghoon,Ahn, Younggil,Park, Hyun-Ju,Kim, Ha Hyung,Kim, Dae Kyong
supporting information, p. 847 - 851 (2021/04/19)
Apoptosis inhibitor (IAP) proteins are overexpressed in many cancers and implicated in tumor growth, so the development of antagonist that disrupts with the binding of IAP to their partner protein is a promising therapeutic strategy. In an effort to incre
