77542-54-2

Usage

Uses

Used in Chemical Analysis:
5-nitro-2,3-dihydroxynaphthalene is used as a chromogenic reagent for the detection of aldehyde and ketone functional groups. Its ability to react with these functional groups allows for the identification and quantification of aldehydes and ketones in chemical samples.
Used in Scientific Research:
5-nitro-2,3-dihydroxynaphthalene is employed in various chemical reactions and scientific research due to its unique properties. Its reactivity with specific functional groups makes it a valuable tool for studying chemical reactions and mechanisms.
Used in Dye and Pigment Production:
5-nitro-2,3-dihydroxynaphthalene is used in the production of dyes and pigments due to its intense color and stability. Its chemical structure contributes to the vibrant hues and long-lasting properties of the dyes and pigments, making it a preferred choice in the industry.
Safety Precautions:
It is important to handle 5-nitro-2,3-dihydroxynaphthalene with caution as it is toxic and potentially harmful if not used properly. Proper safety measures, such as wearing protective gear and working in a well-ventilated area, should be taken to minimize the risk of exposure and ensure safe handling of this chemical compound.

Upstream product

• 22426-45-5 2,3-bis(methylsulfonyloxy)naphthalene 
• 92-44-4 2,3-naphthalenediol 
• 56517-24-9 6,7-bis(methylsulfonyloxy)-1-nitronaphthalene 

Downstream Products

• 3606-45-9 dihydrosanguinarine 
• 5578-73-4 sanguinarine chloride 
• 522-30-5 norsanguinarine 
• 856065-25-3 6-nitro-2,3-dihydronaphtho[2,3-b][1,4]dioxine 
• 52401-42-0 1-amino-6,7-dimethoxynaphthalene 
• 1235871-14-3 C₃₃H₂₆NO₄⁽¹⁺⁾*Cl^(1-) 
• 1235871-74-5 N-(4-(biphenyl-4-yl)-6,7-dimethoxynaphthalen-1-yl)-5-bromo-N-methylbenzo[1,3]dioxole-4-carboxamide 
• 1235871-73-4 N-(4-(biphenyl-4-yl)-6,7-dimethoxynaphthalen-1-yl)-5-bromobenzo[1,3]dioxole-4-carboxamide 
• 1235871-75-6 7-(biphenyl-4-yl)-9,10-dimethoxy-12-methylbenzo[1,3]dioxolo[4,5]phenanthridin-13(12H)-one 
• 1235871-71-2 1-(N-tert-butoxycarbonylamino)-4-biphenyl-6,7-dimethoxynaphthalene 
• 1235871-72-3 4-(biphenyl-4-yl)-6,7-dimethoxynaphthalen-1-amine 
• 1235871-34-7 2,3-dimethoxy-5-nitro-1-phenylnaphthalene 
• 1225383-52-7 2-iodo-4-isopropoxy-3-methoxy-N-(methoxymethyl)-N-(6,7-methylenedioxy-1-naphthyl)benzamide 
• 181634-60-6 6-bromo-2,3-dimethoxy-N-methyl-N-(6,7-methylenedioxynaphthalen-1-yl)benzamide 

Relevant academic research and scientific papers

Synthesis of 2,3,9,10-Tetraoxygenated benzo[c]phenanthridine derivatives via palladiummediated aryl-Aryl coupling reaction

Two 2,3,9,10-Tetraoxygenated benzo[c]phenanthridine alkaloids, 1 2, originally reported as zanthoxyline and broussonpapyrine, respectively, were synthesized using the Pd-mediated intramolecular aryl-Aryl coupling reaction as the key step.

Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives

Antibiotic resistance has prompted efforts to discover antibiotics with novel mechanisms of action. FtsZ is an essential protein for bacterial cell division, and has been viewed as an attractive target for the development of new antibiotics. Sanguinarine is a benzophenanthridine alkaloid that prevents cytokinesis in bacteria by inhibiting FtsZ self-assembly. In this study, a series of 5-methylbenzo[c]phenanthridinium derivatives were synthesized and evaluated for antibacterial activity against Staphylococcus aureus and Enterococcus faecalis. The data indicate that the presence of a 1- or 12-phenyl substituent on 2,3,8,9-tetramethoxy-5-methylbenzo[c]phenanthridinium chloride significantly enhances antibacterial activity relative to the parent compound or sanguinarine.

BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS

The present invention provides compounds of formula I: formula (I) wherein X1- X4 and R1-R12 have any of the values defined in the specification, as well as salts and prodrugs thereof, which inhibit major molecu

A convenient synthesis of benzo[c]phenanthridine alkaloid, chelerythrine, by the palladium-assisted internal biaryl coupling reaction

Total synthesis of chelerythrine, a benzo[c]phenanthridine alkaloid, was accomplished via the internal aryl-aryl coupling reaction of halo-amide (4) by the palladium-assisted cyclization reaction.

SYNTHESIS OF FAGARONINE

Alkaloids fagaronine (I), dihydrofagaronine (XXV) and oxyfagaronine (XXVI) were synthesized from 2,3-dihydroxynaphthalene (II) and 2-bromo-4,5-dimethoxybenzaldehyde (XI), the key synthetic steps being the preparation of 2-hydroxy-3-methoxy-5-nitronaphthal