77548-31-3

Basic information

• Product Name: 2-Cyclohexene-1-carboxylic acid, 2-methyl-4-oxo-6-phenyl-, ethyl ester
• CAS NO: 77548-31-3
• Molecular Formula: C16H18O3
• Molecular Weight: 258.317
• Mol File: 77548-31-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexene-1-carboxylic acid, 2-methyl-4-oxo-6-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexene-1-carboxylic acid, 2-methyl-4-oxo-6-phenyl-, ethyl ester(77548-31-3)
• EPA Substance Registry System: 2-Cyclohexene-1-carboxylic acid, 2-methyl-4-oxo-6-phenyl-, ethyl ester(77548-31-3)

Safety Data

• Hazardous Substances Data: 77548-31-3(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 1896-62-4 (E)-benzalacetone 
• 100-52-7 benzaldehyde 
• 17572-39-3 2,4-diethoxycarbonyl-5-hydroxy-5-methyl-3-phenylcyclohexanone 

Downstream Products

• 1072098-06-6 5-allyloxy-3-methyl-4-phenylaminobiphenyl-2-carboxylic acid ethyl ester 
• 1190367-16-8 6-(phenyl)-7-methyl-9-ethyl-5,6-dihydro-2H-benzo[b][1,4]oxazocine-8-carboxylic acid ethyl ester 
• 1410070-75-5 ethyl 5-(4-iodophenylamino)-3-methylbiphenyl-2-carboxylate 
• 1410070-74-4 ethyl 5-(2-iodo-4-methylphenylamino)-3-methylbiphenyl-2-carboxylate 
• 1410071-10-1 ethyl 5-(2-chloro-4-methylphenylamino)-3-methylbiphenyl-2-carboxylate 
• 1410071-11-2 ethyl 5-{2-chloro-5-(trifluoromethyl)phenylamino}-3-methylbiphenyl-2-carboxylate 
• 1316834-21-5 C₁₆H₁₆O₄ 
• 1247042-31-4 ethyl 4-benzyl-5-hydroxy-3-methyl-biphenyl-2-carboxylate 
• 1247042-10-9 C₂₃H₂₁NO₅ 
• 1097633-79-8 4-methyl-6-phenyl-6,7-dihydro-1H-benzotriazole-5-carboxylic acid ethyl ester 
• 1097633-93-6 3-diazo-2-methyl-4-oxo-6-phenyl-cyclohex-1-enecarboxylic acid ethyl ester 

Relevant articles and documents

Palladium-Catalyzed Tandem γ-Arylation/Aromatization of Cyclohex-2-En-1-One Derivatives: A Route to 3,4-Dihydroanthracen-1(2H)-Ones

An intramolecular palladium-catalyzed tandem γ-arylation/aromatization reaction of cyclohex-2-en-1-one derivatives was developed. This work provides a simple and efficient approach for the construction of substituted 3,4-dihydroanthracen-1(2H)-ones in good yields with a broad substrate scope. (Figure presented.).

Base-mediated aerobic oxidation of Hagemann's ester: Competitive hydroxylation at C-1 and C-3 positions

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High-yielding synthesis of Nefopam analogues (functionalized benzoxazocines) by sequential one-pot cascade operations

An efficient amine-/ruthenium-catalyzed three-step process for the synthesis of Nefopam analogues was achieved through combinations of cascade enamine amination/iso-aromatization/allylation and diene or enyne metathesis as key steps starting from functionalized Hagemann's esters. In this communication, we discovered the application of ruthenium-catalysis on olefins containing free amines without in situ formation of salts.