17572-39-3

Basic information

• Product Name: diethyl 4-hydroxy-4-Methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate
• Synonyms: diethyl 4-hydroxy-4-Methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate;2,4-Dicarbethoxy-5-hydroxy-5-methyl-3-phenylcyclohexanone;NSC 140610;Diethyl 4-hydroxy-4-methyl-6-oxo-2-phenyl-1,3-cyclohexanedicarboxylate
• CAS NO: 17572-39-3
• Molecular Formula: C₁₉H₂₄O₆
• Molecular Weight: 348.39026
• Mol File: 17572-39-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 155-158℃ (ethanol )
• Boiling Point: 483.6°Cat760mmHg
• Flash Point: 167.4°C
• Appearance: /
• Density: 1.198g/cm³
• Vapor Pressure: 3.64E-10mmHg at 25°C
• Refractive Index: 1.528
• Storage Temp.: 2-8°C
• CAS DataBase Reference: diethyl 4-hydroxy-4-Methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 4-hydroxy-4-Methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate(17572-39-3)
• EPA Substance Registry System: diethyl 4-hydroxy-4-Methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate(17572-39-3)

Safety Data

• Hazardous Substances Data: 17572-39-3(Hazardous Substances Data)

Usage

Description

Diethyl 4-hydroxy-4-methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate is a chemical compound with the molecular formula C19H24O6. It is a derivative of phenylcyclohexane-1,3-dicarboxylic acid, featuring a phenyl group, two ester groups, an oxo group, and a hydroxy group. diethyl 4-hydroxy-4-Methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate is commonly utilized in organic synthesis and pharmaceutical research due to its cyclohexane ring structure and carboxylate groups, which are prevalent in many bioactive compounds. Its ester groups also make it a valuable building block for the synthesis of more complex molecules. However, it is essential to handle this chemical substance with care and follow appropriate safety precautions.

Uses

Used in Organic Synthesis:
Diethyl 4-hydroxy-4-methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate is used as a building block in organic synthesis for the creation of more complex molecules. Its ester groups facilitate the synthesis process, making it a versatile component in the development of new organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, diethyl 4-hydroxy-4-methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate is used as a starting material or intermediate in drug development. Its cyclohexane ring structure and carboxylate groups are common motifs in bioactive compounds, which may contribute to the discovery of new therapeutic agents.
Used in Drug Development:
Due to its potential as a component of bioactive compounds, diethyl 4-hydroxy-4-methyl-6-oxo-2-phenylcyclohexane-1,3-dicarboxylate is used in drug development to explore its properties and applications in creating new pharmaceuticals. Its unique structure may offer novel therapeutic opportunities in various medical fields.

InChI:InChI=1/C19H24O6/c1-4-24-17(21)15-13(20)11-19(3,23)16(18(22)25-5-2)14(15)12-9-7-6-8-10-12/h6-10,14-16,23H,4-5,11H2,1-3H3

Upstream product

• 2538-76-3 1,1'-benzylidenedipiperidine 
• 141-97-9 ethyl acetoacetate 
• 100-52-7 benzaldehyde 
• 64-17-5 ethanol 
• 620-80-4 ethyl 2-benzylidene acetoacetate 
• 141-52-6 sodium ethanolate 
• 538-51-2 benzylidene phenylamine 
• 31771-33-2 2-phenyl-4,4,6-trimethyltetrahydro-(2H)-1,3-oxazine 
• 7740-33-2 ethyl 3-thioxobutanoate 
• 100-46-9 benzylamine 
• 74979-92-3 6-[(E)-4-Chloro-phenylimino]-4-hydroxy-4-methyl-2-phenyl-cyclohexane-1,3-dicarboxylic acid diethyl ester 
• 36276-69-4 2-methyl-2-piperidino-1-ethoxycarbonylethene 
• 60-29-7 diethyl ether 
• 870-85-9 ethyl 3-methylaminocrotonate 

Downstream Products

• 127703-64-4 6-Amino-4-hydroxy-4-methyl-2-phenyl-cyclohexane-1,3-dicarboxylic acid diethyl ester 
• 127703-60-0 4,6-Dihydroxy-4-methyl-2-phenyl-cyclohexane-1,3-dicarboxylic acid diethyl ester 
• 127703-70-2 4-Hydroxy-6-[(Z)-hydroxyimino]-4-methyl-2-phenyl-cyclohexane-1,3-dicarboxylic acid diethyl ester 
• 143210-61-1 6-Methyl-3-oxo-4-phenyl-3,3a,4,5-tetrahydro-benzo[c]isoxazole-5-carboxylic acid ethyl ester 
• 79988-78-6 7-Methyl-4-oxo-5-phenyl-2-thioxo-2,3,4,4a,5,6-hexahydro-quinazoline-6-carboxylic acid ethyl ester 
• 143210-72-4 2-Amino-7-methyl-4-oxo-5-phenyl-5,6-dihydro-4H-benzo[d][1,3]thiazine-6-carboxylic acid ethyl ester 
• 124502-20-1 8-Hydroxy-8-methyl-5-oxo-6-phenyl-5,5a,6,7,8,9-hexahydro-4b,10,11-triaza-benzo[b]fluorene-7-carboxylic acid ethyl ester 
• 143210-85-9 4-Amino-9-methyl-6-oxo-7-phenyl-7,8-dihydro-6H-pyrido[1,2-a]quinazoline-8-carboxylic acid ethyl ester 
• 124502-22-3 8-Hydroxy-8-methyl-5-oxo-6-phenyl-5,5a,6,7,8,9-hexahydro-[1,2,4]triazolo[3,4-b]quinazoline-7-carboxylic acid ethyl ester 
• 5337-88-2 3-methyl-5-phenyl-2-cyclohexen-1-one 
• 77548-31-3 2-methyl-4-oxo-6-phenyl-cyclohex-2-enecarboxylic acid ethyl ester 
• 95486-25-2 diethyl 5-methyl-3?oxo-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2,6-dicarboxylate 
• 4165-96-2 3-phenylglutaric acid 
• 19419-23-9 2,2'-phenylmethylene-bis(5,5-dimethylcyclohexane-1,3-dione) 

Relevant articles and documents

A detailed investigation into the one-pot cascade reaction of ethyl 3,9-dimethyl-7-phenyl-6H-dibenzo-[b,d]pyran-6-one-8-carboxylate with phenylhydrazine

Abstract: When synthesizing cyclohexane-annulated pyrazolones from a cyclohexonedicarboxylate derivative with phenylhydrazine under the catalysis of sulfuric acid in the air, up to five products were finally obtained from the one-pot procedure. Among the

An efficient regioselective synthesis of functionalized biphenyls via sequential reactions of aromatic aldehydes and β-keto esters or ketones

Knoevenagel/Michael/Aldol reactions of aromatic aldehydes and β-keto esters/ketones in a sequential manner yielded intermediate cyclohexanones in good yields. The latter, on oxidative aromatization with iodine, afforded functionalized biphenyls with at le

Microwave assisted rapid and efficient synthesis of 2,1-benzoisoxazoles

A simple extremely fast and high yielding protocol has been developed for the synthesis of 2,1-benzisoxazoles under microwave irradiation.