77563-68-9Relevant academic research and scientific papers
Three-component reaction between isocyanides, aliphatic amines and elemental sulfur: Preparation of thioureas under mild conditions with complete atom economy
Nguyen, Thanh Binh,Ermolenko, Ludmila,Al-Mourabit, Ali
, p. 3172 - 3179 (2015/01/09)
The reaction of isocyanides with aliphatic amines in the presence of elemental sulfur was found to proceed efficiently at, or near, room temperature to produce thioureas in excellent yields and with complete atom economy.
A convenient route to cyanoguanidines
Novak, Lajos,Hanania, Michel,Kovacs, Peter,Kovacs, Csilla Erika,Kolonits, Pal,Szantay, Csaba
, p. 1757 - 1766 (2007/10/03)
A facile and versatile method for the preparation of cyanoguanidines 7 from amines 3 and isothiocyanates 4 via a methylation, cyanamide-treatment sequence is described.
Influence of Substituents on the Synthesis of Thiazolidinones
Sabu, M.,Garnaik, B. K.,Behera, Rajani K.
, p. 779 - 781 (2007/10/02)
The influence of substituents (subunits) in the synthesis of thiazolidinones by the reaction of unsymmetrical thioureas with monochloroacetic acid in ethanol has been rationalised by the characterisation of the hydrolysis products of the resulting thiazolidinones.The formation of thiol from thiourea, which is the key intermediate in thiazolidinone synthesis, invariably involves the -NH- group adjacent to more electron withdrawing subunits.
