77597-96-7Relevant academic research and scientific papers
Exploring the reactivity of 1,5-disubstituted sulfonyl-triazoles: Thermolysis and Rh(II)-catalyzed synthesis of α-sulfonyl nitriles This article is dedicated to Professor Paul Wender for both his creative contributions to synthetic organic chemistry and u
Meza-Avi?a, Maria Elena,Patel, Mudita Kishor,Croatt, Mitchell P.
, p. 7840 - 7846 (2013/08/23)
The reactivity of a series of 1,5-disubstituted sulfonyl-triazoles was explored using either thermolytic or metal-catalyzed conditions. Both the thermolysis and the Rh(II)-catalyzed reactions led to the synthesis of α-sulfonyl-nitriles, which presumably o
Enantioselective organocatalytic approach to the synthesis of α,α-disubstituted cyanosulfones
Cid, M. Belén,López-Cantarero, Jesús,Duce, Sara,Ruano, José Luis García
supporting information; experimental part, p. 431 - 434 (2009/04/10)
(Chemical Equation Presented) Optically pure cyano tert-alkyl sulfones have been obtained by organocatalytic enantioselective Michael addition of α-substituted cyanosulfones to vinyl ketones using cinchona alkaloids as catalysts. The best results were obt
Antiinflammation agents
-
Page/Page column 48-49, (2010/02/06)
Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism, infection and cell proliferation. The subject compounds contain a fused heterobicyclic ring.
Synthesis and Stereomutation of Optically Active α-Cyanosulphoxides
Annunziata, Rita,Cinquini, Mauro,Colonna, Stefano,Cozzi, Franco
, p. 614 - 617 (2007/10/02)
Reaction of (-)-menthyl (S)-toluene-p-sulphinate with nitriles and lithium NN-di-isopropylamide (LDA) in 1:1:1 and 1:2:1 ratios affords optically active α-cyano- and α-cyano-β-imino-sulphoxides, respectively. α-Cyanobenzyl sulphoxide racemizes through a h
