77605-69-7

Upstream product

• 116460-49-2 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-ol 
• 100-66-3 methoxybenzene 
• 104-55-2 3-phenyl-propenal 
• 13623-25-1 6-methoxy-2,3-dihydro-1H-inden-1-one 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 132813-90-2 C₂₆H₁₉NO₅ 
• 77605-63-1 2-benzyl-4-methoxyphenylacetic acid 

Relevant academic research and scientific papers

Catalytic Enantioselective [10+4] Cycloadditions

The first peri- and stereoselective [10+4] cycloaddition between catalytically generated amino isobenzofulvenes and electron-deficient dienes is described. The highly stereoselective catalytic [10+4] cycloaddition exhibits a broad scope with high yields,

Synthesis of indenes via aluminum chloride-promoted tandem Friedel-Crafts alkylation of arenes and cinnamaldehydes

A series of substituted indenes were synthesized from arenes and cinnamaldehydes via aluminum chloride-promoted tandem Friedel-Crafts alkylation. The scope and limitation of the tandem reaction were explored. A plausible reaction mechanism is also discuss

Iodine/Et3SiH: A novel reagent system for the synthesis of 3-aryl-1H-indenes from 1,3-diaryl propargyl alcohols

1,3-Diaryl propargyl alcohols undergo smooth intramolecular Friedel-Crafts cyclization with triethylsilane in the presence of 10 mol % iodine 3-aryl-1H-indene derivatives in good yields in short reaction times. This is the first example on the synthesis of substituted indenes from 1,3-diaryl propargyl alcohols. The use of inexpensive and readily available molecular iodine makes this method quite simple, more convenient, and practical.