77614-64-3Relevant articles and documents
Efficient synthesis of 6-amino-2-thiaspiro[3,3]heptane hydrochloride
Lu, Yan,Wang, Jin,Guo, Jianyu,Tang, Yihong,Zhang, Suxia,Tao, Jianwei,Xiong, Lei,Li, Xiujie,Luo, Jingyi
, p. 1 - 4 (2015)
A novel compound 6-amino-2-thiaspiro[3,3]heptane hydrochloride was synthesized in nine steps using 2,2-bis(bromomethyl)-1,3-propanediol as starting material, with an overall yield of 31%.
1-(1-CYCLOBUTYL-4-PIPERIDINYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE ML RECEPTOR AND THEIR USE IN MEDICINE
-
, (2008/12/04)
Compounds of formula I or a salt thereof are provided wherein R4, R5, R6, Q, L and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic disorders and cognitive impairments are disclosed. The invention further discloses pharmaceutical compositions comprising the compounds.