776316-01-9Relevant academic research and scientific papers
Stereocontrolled synthesis of the ABCDE ring moiety of ciguatoxin CTX3C
Kobayashi, Shoji,Takahashi, Yusuke,Komano, Kazuo,Alizadeh, Babak H.,Kawada, Yuuya,Oishi, Tohru,Tanaka, Shin-Ichiro,Ogasawara, Yoshihiro,Sasaki, Shin-Ya,Hirama, Masahiro
, p. 8375 - 8396 (2007/10/03)
The ABCDE ring moiety of ciguatoxin CTX3C, a major causative agent of ciguatera poisoning, was stereoselectively synthesized. The key transformations are a chiral auxiliary-based asymmetric alkylation and an asymmetric aldol condensation, which controlled
