777087-96-4

Upstream product

• 1030359-46-6 (3'R,1R,4R,7R)-1-[4-(benzyloxycarbonyl)phenyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl 2-(benzyloxycarbonyl)-2-azabicyclo[2.2.2]oct-5-ene-7-carboxylate 
• 777088-07-0 (R)-benzyl 4-(3-acryloyloxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)-benzoate 
• 737762-29-7 (+/-)-benzyl 4-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)benzoate 
• 777087-93-1 (1S,3'R)-[1-(4-benzyloxycarbonylphenyl)-4,4-dimethyl-2-oxopyrrolidin-3-yl] 4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate 
• 777087-95-3 (R)-benzyl 4-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)benzoate 
• 862248-97-3 (3'R,1S,2R)-N-(4'-benzyloxycarbonylphenyl)-4',4'-dimethyl-2'-oxopyrrolidin-3'-yl 2-(benzyloxycarbonylamino)cyclohex-3-ene-1-carboxylate 
• 862248-96-2 (3'R,1R,2S)-N-(4'-benzyloxycarbonylphenyl)-4',4'-dimethyl-2'-oxopyrrolidin-3'-yl 2-(benzyloxycarbonylamino)cyclohex-3-ene-1-carboxylate 

Downstream Products

• 121424-36-0 (+)-(1R)-4-methyl-cyclohex-3-enecarboxylic acid 
• 102208-60-6 (S)-4-methyl-3-cyclohexene-1-carboxylic acid 

Relevant academic research and scientific papers

Asymmetric Diels-Alder reaction of aminodienes with a nonracemic acrylate bound to rink resin: A comparison of these reactions with their solution-state analogues

The asymmetric Diels-Alder reactions between (3R)-4,4-dimethyl-2- oxopyrrolidin-3-yl acrylate derivatives and three N-Z-protected 1-aminodienes have been investigated both in solution and on a solid support. Comparable results for each reaction were obser

(R)-(4-(Benzyloxycarbonylphenyl)-3-hydroxy-4,4-dimethyl-2-pyrrolidinone) acrylate derivative as a chiral dienophile for the synthesis of enantiopure 2-aminocyclohexane carboxylic acids

An asymmetric Diels-Alder reaction between the enantiopure (R)-benzyl-4-(3-acryloyloxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)-benzoate (R)-2 and the N-Z-aminodiene 3 proceeded with total endo diastereoselectivity and was facially controlled in favour of the (

(R)- or (S)-4-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)benzoic acid as a new chiral auxiliary for solid phase asymmetric Diels-Alder reactions

The synthesis of enantiopure (R)- and (S)-4-(3-hydroxy-4,4-dimethyl-2- oxopyrrolidin-1-yl)benzoic acid is described and the corresponding supported chiral acrylate derivative has been used as a dienophile in solid phase asymmetric Diels-Alder reactions wi