7773-69-5 Usage
Uses
Used in Pharmaceutical Research and Development:
4-Benzylpiperazine-1-carboxamidine hemisulfate is used as a research compound for its potential in treating neurological disorders due to its enhanced pharmacological and biological activities. It is particularly valuable in the development of new drug candidates that target the central nervous system.
Used in Medicinal Chemistry Studies:
In the field of medicinal chemistry, 4-Benzylpiperazine-1-carboxamidine hemisulfate is used as a tool to study the structure-activity relationships of benzylpiperazine derivatives. Its unique properties allow researchers to explore its interactions with various biological targets, potentially leading to the discovery of novel therapeutic agents.
Used in Drug Synthesis:
4-Benzylpiperazine-1-carboxamidine hemisulfate is used as a precursor in the synthesis of new pharmaceutical compounds. Its versatile chemical structure and enhanced solubility due to its hemisulfate form make it an ideal starting material for the development of innovative drugs.
Used in Testing Procedures:
In the context of testing procedures, 4-Benzylpiperazine-1-carboxamidine hemisulfate is used to evaluate the efficacy and safety of new drug candidates. Its psychoactive properties and potential neurological effects make it a relevant compound for assessing the impact of new treatments on the central nervous system.
Used in Neurological Disorder Treatment Research:
4-Benzylpiperazine-1-carboxamidine hemisulfate is used as a research compound in the investigation of potential treatments for various neurological disorders. Its pharmacological profile and ability to modulate specific biological pathways make it a promising candidate for further exploration in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 7773-69-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,7 and 3 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7773-69:
(6*7)+(5*7)+(4*7)+(3*3)+(2*6)+(1*9)=135
135 % 10 = 5
So 7773-69-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N4/c13-12(14)16-8-6-15(7-9-16)10-11-4-2-1-3-5-11/h1-5H,6-10H2,(H3,13,14)
7773-69-5Relevant articles and documents
Synthesis and antitumor activities of a new series of 4,5-dihydro-1H- thiochromeno[4,3-d]pyrimidine derivatives
Guo, Dexiang,Liu, Yajing,Li, Ting,Wang, Nan,Zhai, Xin,Hu, Chun,Gong, Ping
experimental part, p. 347 - 351 (2012/08/08)
A new series of 4,5-dihydro-1H-thiochromeno[4,3-d ]pyrimidine derivatives have been designed and synthesized. The antitumor activities of the target compounds have been evaluated in vitro against two human cancer cell lines including A549 (human alveolar adenocarcinoma cell) and H460 (human lung cancer) by MTT assay. Most of the target compounds exhibited significant antitumor activities against A549 and H460 cancer cell lines. The most potent compound 4-(benzo[d][1,3]dioxol-5-yl)-8,9-difluoro-2-(4-methylpiperazin-1-yl)-4, 5-dihydro-1H-thiochromeno[4,3-d]pyrimidine (CH05) (IC50 = 0.44 μM, 3.07 μM) was 2.0 and 8.4 times more active than gefitinib (IC50 = 0.89 μM, 16.81 μM) against A549 and H460 cell lines, respectively.
A novel, facile methodology for the synthesis of N,N′-bis(tert-butoxycarbonyl)-protected guanidines using polymer-supported carbodiimide
Guisado, Olga,Martínez, Sonia,Pastor, Joaquín
, p. 7105 - 7109 (2007/10/03)
A novel methodology for the synthesis of guanidines from amines has been developed using polymer assisted synthesis, potentially allowing the preparation of series of compounds in a high throughput manner. The methodology comprises the use of polymer-supported carbodiimide as the activating agent for N,N′-bis(tert-butoxycarbonyl) thiourea with polymer-supported trisamine as a scavenger, followed by deprotection with trifluoroacetic acid. For the first time, polymer-supported carbodiimide has been utilized as an activating agent to synthesize guanidines.
