77744-14-0

Basic information

• Product Name: 1-Phenyl-1-(2-pyridyl)-2-propen-1-ol
• Synonyms: 1-Phenyl-1-(2-pyridyl)-2-propen-1-ol
• CAS NO: 77744-14-0
• Molecular Weight: 211.263
• Mol File: 77744-14-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Phenyl-1-(2-pyridyl)-2-propen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-1-(2-pyridyl)-2-propen-1-ol(77744-14-0)
• EPA Substance Registry System: 1-Phenyl-1-(2-pyridyl)-2-propen-1-ol(77744-14-0)

Safety Data

• Hazardous Substances Data: 77744-14-0(Hazardous Substances Data)

Upstream product

• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 593-60-2 Vinyl bromide 
• 1826-67-1 vinyl magnesium bromide 
• 31796-72-2 phenyl(2-pyridinyl)methanol 

Downstream Products

• 82244-23-3 3-phenyl-3-(pyridin-2-yl)prop-2-en-1-ol 
• 101350-47-4 5-oxo-5-phenyl-4-(pyridin-2-yl)pentanenitrile 
• 35344-68-4 dimethyl-(3-phenyl-3-pyridin-2-yl-allyl)-amine 
• 35344-69-5 dimethyl-(3t-phenyl-3c-[2]pyridyl-allyl)-amine 
• 82244-32-4 3-Morpholin-4-yl-1-phenyl-indolizine 
• 82244-33-5 1-Phenyl-3-piperidin-1-yl-indolizine 
• 82244-34-6 Diethyl-(1-phenyl-indolizin-3-yl)-amine 
• 82244-40-4 3-phenyl-3-(2-pyridyl)-2-propenal 
• 77744-22-0 Acetic acid 1-phenyl-1-pyridin-2-yl-allyl ester 

Relevant articles and documents

Photo-induced phosphorus radical involved semipinacol rearrangement reaction: Highly synthesis of γ-oxo-phosphonates

Hydroxyphosphoric acids display the unique biological activities, and they have some attractive prospects as clinical drug moleculars. Herein, a new approach for the synthesis of γ-oxo-phosphonates (the precursor of hydroxyphosphoric acid) has been established through the semipinacol rearrangement tactic involved the photo-induced phosphorus radical process. Most important, this transformation is avoid of the external oxidants, and occurs very well under the sunlight irradiation, meanwhile the γ-oxo-phosphonate was easily derivatized to obtain γ-hydroxyphosphoric acid, thus highlights the synthesis value of this method.

Synthesis of 3-Aryl-3-pyridylallylamines Related to Zimelidine via Palladium-Catalyzed Amination

Reaction of aryl pyridyl ketones 1 with vinylmagnesium bromide followed by acetylation of the products 2 with acetic anhydride/Et3N and with 4-(dimethylamino)pyridine (DMAP) as a catalyst gave acetates 3 in high yields.Treatment of acetates 3 with dimethylamine in the presence of a palladium catalyst produced a mixture of E and Z isomers of 3-aryl-3-pyridylallylamines 4.