77745-28-9

Usage

Uses

Used in Organic Synthesis:
(1S,4R)-4-AMINO-CYCLOPENT-2-ENYL-METHANOL HYDROCHLORIDE is used as a building block in organic synthesis for the creation of biologically active molecules. Its unique structure allows for the development of new compounds with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (1S,4R)-4-AMINO-CYCLOPENT-2-ENYL-METHANOL HYDROCHLORIDE is used as a reagent in the preparation of other compounds. Its properties make it a valuable component in the synthesis of pharmaceuticals, potentially leading to the discovery of new drugs.
Used as a Substrate in Enzyme-Catalyzed Reactions:
(1S,4R)-4-AMINO-CYCLOPENT-2-ENYL-METHANOL HYDROCHLORIDE may also serve as a substrate for enzyme-catalyzed reactions, which can be crucial in the study of enzymatic mechanisms and the development of enzyme inhibitors or activators.
Used in the Development of New Drugs:
Due to its potential biological activities, (1S,4R)-4-AMINO-CYCLOPENT-2-ENYL-METHANOL HYDROCHLORIDE may be employed in the development of new drugs for medical applications. Its unique structure and properties could contribute to the creation of innovative therapeutic agents.

Upstream product

• 77745-25-6 cis-4-amino-2-cyclopentenecarboxylic acid methyl ester hydrochloride 
• 49805-30-3 2-azabicyclo[2.2.1.]hept-5-en-3-one 
• 172720-97-7 (+/-)-tert-butyl (1RS,4SR)-4-(hydroxymethyl)cyclopent-2-enylcarbamate 
• 61865-62-1 cis-4-aminocyclopent-2-nene-1-carboxylic acid hydrochloride 
• 76909-91-6 rel-(1R,5R)-5-(hydroxymethyl)cyclopent-2-en-1-ol 

Downstream Products

• 61865-50-7 (+/-)-(1RS,4SR)acetic acid 4-acetylamido-cyclopent-2-enyl-methyl ester 

Relevant academic research and scientific papers

Syntheses of carbocyclic aminonucleosides and (-)-epi-4′-carbocyclic puromycin: application of palladium(0)/indium iodide-allylations and tethered aminohydroxylations

Carbocyclic aminonucleosides and epi-4′-carbocyclic puromycin were prepared from an acylnitroso-derived hetero Diels-Alder cycloadduct. Pd(0)/InI-mediated allylations of a formyl species were used to install the 4′-hydroxymethyl group. A tethered aminohydroxylation strategy was employed to install the cis-2′,3′-aminoalcohol moiety with complete regio- and diastereocontrol.

A facile synthesis of cis-4-amino-2-cyclopentene-1-methanol, a key intermediate for the synthesis of carbocyclic nucleosides

A number of carbocyclic nucleosides can be synthesized from (±)-cis-4-amino-2-cyclopentene-1-methanol (3). Carbocyclic amino alcohol 3 is a key intermediate that makes possible the efficient synthesis of the carbocyclic nucleosides. In this study we wish to report an efficient synthesis of carbocyclic amino alcohol 3 from inexpensive and readily available starting material. The synthetic route employed cyclopentadiene (4) as a starting material and proceeded in 38% overall yield through 6 steps involving a hetero Diels-Alder reaction and an aza-Claisen rearrangement.

Carbocyclic Sugar Amines: Synthesis and Stereochemistry of Racemic α- and β-Carbocyclic Ribofuranosylamine, Carbocyclic Lyxofuranosylamine, and Related Compounds

The facile and stereoselective synthesis of racemic carbocyclic β-ribofuranosylamine, carbocyclic β-lyxofuranosylamine, and related 2,3-cis-dihydroxy carbocyclic pentofuranosylamines is reported.In addition, the synthesis, isolation, and base-catalyzed epimerization of methyl cis-4-aminocyclopent-2-enecarboxylate are described.The epimerization at C(1) followed by stereoselective cis hydroxylation provides for the first time access to the racemic carbocyclic α-pentofuranosylamines.