77862-52-3Relevant academic research and scientific papers
Lewis acid-promoted addition of methylenecyclopropanes to aldehydes and ketones
Miura, Katsukiyo,Takasumi, Mizuki,Hondo, Takeshi,Saito, Hiroshi,Hosomi, Akira
, p. 4587 - 4590 (1997)
In the presence of TiCl4, methylenecyclopropane (1a) easily reacted with aliphatic aldehydes to give the β-(chloromethyl)allylated products 2 in good yields along with a small amount of the methylenetetrahydrofurans 3. The reaction with chiral α- and β-alkoxy aldehydes proceeded with high levels of chelation control.
Palladium-Catalyzed Trimethylenemethane Reaction To Form Methylenetetrahydrofurans. Aldehyde and Ketone Substrates and the Tin Effect
Trost, Barry M.,King, Steven A.,Schmidt, Thomas
, p. 5902 - 5915 (2007/10/02)
The palladium-catalyzed trimethylenemethane (TMM) cycloaddition of carbonyl compounds has been shown to have a strong dependence upon the presence of cocatalysts such as tri-n-butyltin acetate, di-n-butyltin diacetate, or trimethyltin acetate.High-yieldin
A Two Catalyst System For Cycloaddition of a Trimethylenemethane Fragment to Aldehydes
Trost, Barry M.,King, Steven A.
, p. 5971 - 5974 (2007/10/02)
The cycloaddition of 2-trimethylsilylmethylallyl acetate to aldehydes is co-catalyzed by a Pd(0) complex and a trialkyltin acetate.
Iodine(III)-Mediated Intramolecular Cyclization of Hydroxy Allylsilanes: Synthesis of 5- or 6-Membered β-Methylene Cyclic Ethers
Ochiai, Masahito,Fujita, Eiichi,Arimoto, Masao,Yamaguchi, Hideo
, p. 989 - 997 (2007/10/02)
Oxidative cyclization of hydroxy allylsilanes utilizing the combination of a hypervalent organoiodine compound and a Lewis acid was studied.The allylsilanes 4, prepared from the γ-lactones 1 via conversion to the bis(trimethylsilylmethyl)carbinols 3, on t
Hypervalent Organoiodine Chemistry: a New Synthesis of β-Methylene Cyclic Ethers
Ochiai, Masahito,Fujita, Eiichi,Arimoto, Masao,Yamaguchi, Hideo
, p. 1108 - 1109 (2007/10/02)
The allylsilanes (1), containing suitably-substituted hydroxy-groups, on treatment with iodosylbenzene in the presence of BF3-Et2O in an ether solvent, give 5- or 6-membered β-methylene cyclic ethers (3) in good yields, presumably via the highly reactive
