77879-90-4 Usage
Uses
Used in Pharmaceutical Industry:
DC-38-V is used as an antitumor agent for its potent inhibitory effect on the catalytic activity of human topoisomerase II, which plays a crucial role in DNA replication and transcription. It is also used as an antibacterial, antifungal, and antiviral agent due to its broad-spectrum activity against various microorganisms.
Used in Cancer Research:
DC-38-V is used as a photoactivated cross-linker of DNA to histones, which has potential applications in cancer research and the development of novel cancer therapies. Its ability to target and inhibit topoisomerase II makes it a promising candidate for the treatment of various types of cancer.
Used in Antimicrobial Applications:
DC-38-V is used as an antimicrobial agent for its potent activity against bacteria, fungi, and viruses. Its broad-spectrum activity makes it a valuable tool in the development of new antimicrobial drugs to combat drug-resistant infections.
Check Digit Verification of cas no
The CAS Registry Mumber 77879-90-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,8,7 and 9 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77879-90:
(7*7)+(6*7)+(5*8)+(4*7)+(3*9)+(2*9)+(1*0)=204
204 % 10 = 4
So 77879-90-4 is a valid CAS Registry Number.
InChI:InChI=1/C27H26O9/c1-5-12-8-15-19(17(9-12)33-3)14-10-18(34-4)21-16(28)7-6-13(20(21)25(14)36-27(15)32)26-24(31)23(30)22(29)11(2)35-26/h5-11,22-24,26,28-31H,1H2,2-4H3/t11-,22+,23+,24-,26-/m1/s1
77879-90-4Relevant academic research and scientific papers
Structure and stereochemistry or toromycin: Studies of its acid-catalyzed rearrangement
Jain,Simolike,Jackman
, p. 599 - 605 (2007/10/02)
An antibiotic from Streptomyces has been shown to be identical with toromycin and gilvocarcin V. Toromycin has been shown by FT NOE difference spectroscopy to be a C-β-fucofuranoside and to undergo acid-catalyzed rearrangement to an approx. 1:1:2.5 mixture of toromycin and the corresponding C-α-fucofuranoside and C-β-fucopyranoside.
