77889-98-6Relevant academic research and scientific papers
One-pot sequential asymmetric hydrogenation of β-aryl-β-aryloxy acroleins
Liu, Yufeng,Chen, Jianzhong,Zhang, Zhenfeng,Qin, Jian,Zhao, Min,Zhang, Wanbin
supporting information, p. 7099 - 7102 (2016/07/30)
A one-pot sequential asymmetric hydrogenation of β-aryl-β-aryloxy acroleins has been realized for the preparation of chiral 3-aryl-3-aryloxy alcohols with excellent yields and good enantioselectivities. This methodology can be employed in new synthetic routes for the synthesis of fluoxetine, atomoxetine, and related analogues.
Synthesis of benzoxazoles via an amine-catalyzed [4 + 1] annulation
Song, Aiguo,Chen, Xiaobei,Song, Xixi,Zhang, Xinshuai,Zhang, Shilei,Wang, Wei
supporting information, p. 2510 - 2513 (2013/06/27)
An unprecedented simple pyrrolidine catalyzed [4 + 1] annulation reaction of ynals with N-protected-2-aminophenols is reported. The utilization of the unique property and reactivity of the C=C triple bond in ynals leads to two consecutive conjugate additi
Latent Inhibitors. Part 2. Allylic Inhibitors of Alcohol Dehydrogenase
MacInnes, Iain,Schorstein, David E.,Suckling, Colin J.,Wrigglesworth, Roger
, p. 1103 - 1108 (2007/10/02)
The syntheses of a number of 3-substituted prop-2-en-1-ols and -1-als, required for studying the latent inhibition of horse liver alcohol dehydrogenase (E.C. 1.1.1.1), are described.Substituent were chosen to cover a range of alkoxide, phenolate, thiolate
