779339-16-1

Upstream product

• 32085-88-4 3,5-difluorobenzaldehyde 
• 73874-95-0 (piperidin-4-yl)carbamic acid tert-butyl ester 
• 141776-91-2 1-bromomethyl-3,5-difluoro-benzene 

Downstream Products

• 866206-48-6 3-((4-(6-Chlorothieno[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl)methyl)benzoic acid monomaleate 
• 160358-09-8 1-(3,5-difluoro-benzyl)-piperidin-4-ylamine 

Relevant academic research and scientific papers

PIPERIDINYLAMINO-PYRIDAZINES AND THEIR USE AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS

The present invention relates to 6-(piperidin-4-ylamino)pyridazin-3-carbonitriles of formula (I) that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.

New piperidinylamino-thieno[2,3-D] pyrimidine compounds

The invention relates to 5-HT receptor antagonists. Novel piperidinylamino-thieno [2,3-d]pyrimidine compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed.

Piperidinylamino-thieno[2,3-D] pyrimidine compounds

The invention relates to 5-HT receptor modulators, particularly 5-HT2B antagonists. Novel piperidinylamino-thieno [2,3-d] pyrimidine compounds represented by Formula I, II and III, and uses thereof for treating conditions including pulmonary ar