77934-87-3

Basic information

• Product Name: (R)-5-((1R)-MENTHYLOXY)-2(5H)-FURANONE, 98
• Synonyms: (R)-5-((1R)-MENTHYLOXY)-2(5H)-FURANONE, 98;(R)-5-((1R)-menthyloxy)-2(5H)-furanone;(R)-5-[(1R)-Menthyloxy]-2(5H)-furanone;(5R)-5-[[(1R,2S,5R)-5-Methyl-2-isopropyl-cyclohexyl]oxy]-2(5H)-furanone
• CAS NO: 77934-87-3
• Molecular Formula: C₁₄H₂₂O₃
• Molecular Weight: 238.32
• Mol File: 77934-87-3.mol
• Article Data: 19

Chemical Properties

• Melting Point: 78-80 °C(lit.)
• Boiling Point: 120-123 °C0.01 mm Hg(lit.)
• Flash Point: 153.456°C
• Appearance: /
• Density: 1.0500 (rough estimate)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.5800 (estimate)
• CAS DataBase Reference: (R)-5-((1R)-MENTHYLOXY)-2(5H)-FURANONE, 98(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-5-((1R)-MENTHYLOXY)-2(5H)-FURANONE, 98(77934-87-3)
• EPA Substance Registry System: (R)-5-((1R)-MENTHYLOXY)-2(5H)-FURANONE, 98(77934-87-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 77934-87-3(Hazardous Substances Data)

Usage

General Description

(R)-5-((1R)-MENTHYLOXY)-2(5H)-FURANONE, 98 is a chemical compound with a purity of 98%. It is a furanone derivative and has a molecular formula of C11H18O2. (R)-5-((1R)-MENTHYLOXY)-2(5H)-FURANONE, 98 is commonly used in the pharmaceutical and fragrance industries due to its sweet, fruity odor. It is also used as a flavoring agent in food products. The compound is stable under normal conditions and is known for its low toxicity and low environmental impact. Overall, (R)-5-((1R)-MENTHYLOXY)-2(5H)-FURANONE, 98 is a versatile compound with various applications in different industries.

InChI:InChI=1/C14H22O3/c1-9(2)11-5-4-10(3)8-12(11)16-14-7-6-13(15)17-14/h6-7,9-12,14H,4-5,8H2,1-3H3/t10-,11+,12-,14-/m1/s1

Upstream product

• 10449-66-8 5-methoxyfuran-2(5H)-one 
• 2216-51-5 (-)-menthol 
• 2833-30-9 5-ethoxy-2,5-dihydrofuran-2-one 
• 98-01-1 furfural 
• 1575-59-3 4-oxo-crotonic acid 
• 20747-49-3 (-)-neomenthol 
• 201030-32-2 (4S*,5R)-4-(1'-nitro-1'-carbethoxymethyl)-5-((1R)-menthyloxy)-3,4-dihydro-2(5H)-furanone (Z)-(+)-iso-propyl nitronic ester 
• 112968-75-9 (+)-(5S)-5-((+)-menthyl)oxy-2<5H>-furanone 
• 14032-66-7 5-hydroxy-2-(5H)-furanone 

Downstream Products

• 112945-64-9 3-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-3a,4,7,7a-tetrahydro-3H-isobenzofuran-1-one 
• 129297-41-2 (3R,3aR,9aR,9bS)-3-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-3a,4,6,7,8,9,9a,9b-octahydro-3H-naphtho[1,2-c]furan-1-one 
• 127158-55-8 4(R)5(R)-4-(trismethylthiomethyl)-5-(l-menthyloxy)-butyrolactone 
• 135965-90-1 (3R,4R)-3-[(propane-1,3-diyldithio)-(3,4-methylenedioxyphenyl)methyl]-4-[(1R,2S,5R)-2-(1-methylethyl)-5-methyl-1-cyclohexyloxy]butano-4-lactone 
• 117554-03-7 (4R,5R)-5-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-4-((S)-1-phenyl-ethylamino)-dihydro-furan-2-one 
• 117554-03-7 (4S,5R)-5-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-4-((S)-1-phenyl-ethylamino)-dihydro-furan-2-one 
• 129297-45-6 (3R,3aR,5aS,9aS,9bS)-3-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-octahydro-naphtho[1,2-c]furan-1,5-dione 
• 140138-37-0 (-)-(3S,4R,5R)-3-(3',4',5'-trimethoxybenzyl)-4-<3'',4''-methylenedioxy-α,α-bis(phenylthio)benzyl>-5-(1-menthyloxy)butyrolactone 
• 135965-91-2 (-)-(4R,5R)-4-<3',4'-methylenedioxy-α,α-bis(phenylthio)benzyl>-5-(1-menthyloxy)butyrolactone 
• 140160-51-6 (-)-(3S,4R,5R,6R)-3-(3',4',5'-trimethoxy-α-hydroxybenzyl)-4-<3'',4''-methylenedioxy-α,α-bis(phenylthio)benzyl>-5-(1-menthyloxy)butyrolactone 
• 120779-59-1 3a(S)6(R)6a(R)-3-phenyl-6-menthyloxy-3a,4,6,6a-tetrahydro-furo<3,4-d>isoxazol-4-one 
• 151697-35-7 C₃₃H₃₈O₁₀ 

Relevant articles and documents

Four Stereoisomers of 2-Aminomethyl-1-cyclopropanecarboxylic Acid: Synthesis and biological evaluation

Here, we report a practical method for asymmetric synthesis of cyclopropane-fused GABA analogs. Starting from 2-furaldehyde, the cis-isomer (CAMP) was synthesized over 10 steps; (1)- and (+)-CAMP￠HCl were synthesized by employing d- and l-menth

Highly enantioselective synthesis and potential biological activity of chiral novel nucleoside analogues containing adenine and naturally phenol derivatives

This paper described an efficient synthetic strategy for chiral acyclic nucleoside analogues containing both the phenoxy components of some bioactive natural compounds and a heterocyclic base. The phenoxy components with adenine moiety were incorporated into the chiral acyclic nucleoside analogues through two key synthetic tactics. Chiron 5-(R)-menthyloxy-2(5H)-furanone 5 was obtained in good yield from the cheap starting material furfural via a valuable synthetic route. The asymmetric Michael addition of 5 with adenine and the subsequent reduction reaction afforded the key chiral intermediate, 2-(R)-(9′-adeninyl)-1,4-butanediol 8. The absolute configuration of 8 was established by X-ray crystallography. The intermolecular dehydration reaction between 2-(9′-adeninyl)-1,4-butanediol 8 and phenoxy components 9 on treatment with diethyl azodicarboxylate and triphenylphosphine was carried out to give the chiral acyclic nucleoside analogues 1a-1e. The regioselectivity of the reaction was established by NMR methods, especially through 13C NMR shifts and NOE effect observed in the target molecule 1c, as well as by HMBC/HMQC experiments. The target compounds were tested for inhibition of cytopathogenicity against different cancer cells and exhibited potential anticancer activity.

Method for preparing (+)-biotine

The invention relates to a novel method for preparing biotine while using 5-hydroxy-2(5H)-furanone as a starting substance. The invention also relates to a method in which 1-chlorosulfonyl-1,2,2a,3,5,5a-hexa-hydro-3-((1R)-menthyloxy-)-furo[3,4-b]azet-2-on