77940-90-0Relevant academic research and scientific papers
ENANTIOSELECTIVE HANTZSCH DIHYDROPYRIDINE SYNTHESIS VIA METALATED CHIRAL ALKYL ACETOACETATE HYDRAZONES
Enders, Dieter,Mueller, Stephan,Demir, Ayhan S.
, p. 6437 - 6440 (1988)
An efficient, overall enantioselective variant of the Hantzsch synthesis of 4-aryl-1,4-dihydropyridines 5 (ee = 84 - 98percent), important biologically active compounds (e. g. as calcium channel blockers), is described.Key step of the new procedure is the
