77942-13-3

Usage

Preparation

Preparation by methylation of 2,4-dihydroxy- 3-methyl-propiophenone with dimethyl sulfate in the presence of potassium carbonate in refluxing acetone for 48 h (86%).

InChI:InChI=1/C12H16O3/c1-5-10(13)9-6-7-11(14-3)8(2)12(9)15-4/h6-7H,5H2,1-4H3

Upstream product

• 5673-07-4 2,6-dimethoxytoluene 
• 79-03-8 propionyl chloride 
• 608-25-3 2-methylbenzene-1,3-diol 
• 63876-46-0 1-(2,4-dihydroxy-3-methylphenyl)propan-1-one 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 383187-30-2 propionic acid 2,4-dimethoxy-3-methylphenyl ester 
• 117845-03-1 N-[4-(2,4-Dimethoxy-3-methyl-phenyl)-5-methyl-thiazol-2-yl]-benzamide 
• 117845-01-9 N-[4-(2,4-Dimethoxy-3-methyl-phenyl)-5-methyl-thiazol-2-yl]-acetamide 
• 117845-07-5 4-(2,4-Dimethoxy-3-methyl-phenyl)-5-methyl-2-methylsulfanyl-thiazole 
• 117845-05-3 4-(2,4-Dimethoxy-3-methyl-phenyl)-5-methyl-thiazole-2-thiol 
• 117844-99-2 4-(2,4-Dimethoxy-3-methyl-phenyl)-5-methyl-thiazol-2-ylamine 
• 77942-32-6 [3-(2,4-Dimethoxy-3-methyl-phenyl)-2-methyl-3-oxo-propyl]-trimethyl-ammonium; iodide 
• 77941-98-1 1-(2,4-dimethoxy-3-methylphenyl)-2-methylprop-2-en-1-one 
• 383187-77-7 (E)-(2R,6S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-6-[(4S,5R,6R)-2,2,5-trimethyl-6-(2,3,5-trimethoxy-4-methyl-phenyl)-[1,3]dioxan-4-yl]-hept-4-en-3-one 
• 383187-78-8 (R)-4-(tert-Butyl-diphenyl-silanyloxy)-1-[(2R,3R,4S,5R,6R)-4-hydroxy-3,5-dimethyl-6-(2,3,5-trimethoxy-4-methyl-phenyl)-tetrahydro-pyran-2-yl]-3-methyl-butan-2-one 
• 383187-79-9 (2R,3R,4S,5R,6R)-2-[(S)-4-(tert-Butyl-diphenyl-silanyloxy)-3-methyl-butyl]-3,5-dimethyl-6-(2,3,5-trimethoxy-4-methyl-phenyl)-tetrahydro-pyran-4-ol 
• 383187-65-3 (4S,5R,6R)-4-[(S)-2-(4-Methoxy-benzyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-6-(2,3,5-trimethoxy-4-methyl-phenyl)-[1,3]dioxane 
• 383187-47-1 (2R,3S,4S)-3-Hydroxy-5-(4-methoxy-benzyloxy)-2,4-dimethyl-1-(2,3,5-trimethoxy-4-methyl-phenyl)-pentan-1-one 
• 383187-63-1 (1R,2R,3S,4S)-5-(4-Methoxy-benzyloxy)-2,4-dimethyl-1-(2,3,5-trimethoxy-4-methyl-phenyl)-pentane-1,3-diol 

Relevant academic research and scientific papers

Synthesis of the C1-C13 fragment of kendomycin: Atropisomerism around a C-aryl glycosidic bond

The left-hand fragment 2 of the novel antibiotic kendomycin (1) has been synthesized by an aldol addition of a C5 alcohol with a C9-C11 enone. Compound 2 shows an interesting atropisomerism around the C4a-C5-sp2-sp3 bond. The atropis

The Synthesis of Indan-1-ones and Isocoumarins

A flexible synthetic route leading via indan-1-ones to variously methylated and oxygenated isocoumarins is described.The indanones are prepared by alternative routes involving intramolecular Friedel-Crafts cyclisation of arylpropionic acids or pericyclic ring closure of acrylophenones.The influence of substitution on the rate of the pericyclic reaction is assessed.