77995-51-8

Usage

Molecular Structure

The compound has a complex molecular structure that contains a benzothiophene ring fused to a triazolopyrimidine ring, along with two methyl groups at the 2 and 5 positions.

Classification

It is a heterocyclic chemical.

Potential Applications

BTTP is a potentially important building block for the synthesis of various organic compounds and materials, with potential use in pharmaceuticals, materials science, and organic synthesis.

Ongoing Research

The precise properties and potential applications of 2,5-dimethyl-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine are still being studied and developed.

Unique Arrangement of Atoms

The unique arrangement of atoms in this molecule gives it potential for various applications.

Upstream product

• 178685-48-8 N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)acetimidic acid ethyl ester 
• 4651-91-6 3-cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene 
• 78-39-7 Triethyl orthoacetate 
• 77995-54-1 4-hydrazinyl-2-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine 
• 64-19-7 acetic acid 

Downstream Products

• 101130-24-9 2-Methyl-4-((E)-styryl)-7,8,9,10-tetrahydro-6-thia-1,3,3a,5-tetraaza-cyclopenta[c]fluorene 

Relevant academic research and scientific papers

Synthesis and pharmacological evaluation of novel thienopyrimidine and triazolothienopyrimidine derivatives

Novel tricyclic thienopyrimidines (2, 3, 5, 8) and triazole-fused tetracyclic thienopyrimidines (6a-c and 9a-c) were synthesized from the precursor 2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile (1). The structures of newly synthesized compounds were established by spectral and analytical data. The title compounds were screened for analgesic, anti-inflammatory, ulcerogenicity index, and antibacterial activities. Test compounds exhibited significant activity, the compounds (6a-c) and (9a-c) showed more potent analgesic activity, and the compounds (6c) and (9c) showed more potent anti-inflammatory activity than the reference standard Diclofenac Sodium. All the synthesized compounds exhibited remarkable antibacterial activity.

Studies in the Synthesis and Interconversion of Isomeric Triazolothienopyrimidines

4-Hydrazinothienopyrimidines were cyclized with triethyl orthoformate and formic acid to give 1,2,4-triazolothienopyrimidines and 1,2,4-triazolothienopyrimidines depending on the reaction conditions employed.