78-34-2 Hazards Identification
Pictogram(s):
Signal:
Danger
GHS Hazard Statements:
H300: Fatal if swallowed [Danger Acute toxicity, oral]
H311: Toxic in contact with skin [Danger Acute toxicity, dermal]
H330: Fatal if inhaled [Danger Acute toxicity, inhalation]
H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes:
P260, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501
Hazard Classes and Categories:
Acute Tox. 2 *
Acute Tox. 3 *
Aquatic Acute 1
Aquatic Chronic 1
Acute Tox. 2 (100%)
Acute Tox. 3 (100%)
Aquatic Acute 1 (100%)
Aquatic Chronic 1 (100%)
Acute toxicity - category 2
Acute toxicity - category 3
Hazardous to the aquatic environment (acute) - category 1
Hazardous to the aquatic environment (chronic) - category 1
Acute toxicity (Oral) - Category 2
Acute toxicity (Dermal) - Category 2
Acute toxicity (Inhalation: Dusts and mists) - Category 2
Serious eye damage/eye irritation - Category 2B
Specific target organ toxicity - Single exposure - Category 1 (nervous system)
Specific target organ toxicity - Repeated exposure - Category 1 (nervous system)
Hazardous to the aquatic environment (Acute) - Category 1
Hazardous to the aquatic environment (Long-term) - Category 1
Hazards Summary:
Inhalation of high concentrations may cause CNS effects; Cholinesterase inhibitor; [ICSC] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
78-34-2 Usage
Uses
Used in Livestock Protection:
Dioxathion is used as an insecticide for livestock, specifically to protect them from harmful insects that can cause stress, reduce productivity, and spread diseases. Its application helps maintain the health and well-being of animals in farming operations.
Used in Citrus Fruit Production:
In the agricultural industry, particularly for citrus fruits, DIOXATHION is used as an acaricide. This application is crucial for controlling mite populations that can damage the fruit, affect yield, and reduce the overall quality of the produce. By using DIOXATHION, growers can ensure a healthier and more profitable citrus crop.
Air & Water Reactions
Insoluble in water. DIOXATHION is stable in water at a neutral pH.
Reactivity Profile
DIOXATHION is heat sensitive. DIOXATHION may react with iron or tin surfaces. DIOXATHION may be hydrolyzed by strong acids or alkalis. . Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Health Hazard
Very toxic. Probable oral lethal dose for humans is 50-500 mg/kg or between 1 teaspoonful and 1 oz. for a 70 kg (150 lb.) person. It is a cholinesterase inhibitor. Death is primarily due to respiratory arrest arising from failure of the respiratory center, paralysis of respiratory muscles, intense bronchoconstriction, or all three.
Fire Hazard
Shock can shatter container, releasing contents. (Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated to decomposition, DIOXATHION emits highly toxic fumes of oxides of nitrogen, phosphorus, and sulfur. Avoid alkali materials and heat. DIOXATHION is unstable to iron or tin surfaces and when mixed with certain carriers.
Safety Profile
Poison by ingestion,
inhalation, skin contact, and intraperitoneal
routes. Mutation data reported. A
cholinesterase inhibitor. When heated to
decomposition it emits very toxic fumes of
POx, and SOx,. See also PARATHION
Check Digit Verification of cas no
The CAS Registry Mumber 78-34-2 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 78-34:
(4*7)+(3*8)+(2*3)+(1*4)=62
62 % 10 = 2
So 78-34-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H26O6P2S4/c1-5-15-19(21,16-6-2)23-11-12(14-10-9-13-11)24-20(22,17-7-3)18-8-4/h11-12H,5-10H2,1-4H3
