78-34-2

Molecule structure of Dioxathion (CAS NO.78-34-2) :

IUPAC Name: (3-diethoxyphosphinothioylsulfanyl-1,4-dioxan-2-yl)sulfanyl-diethoxy-sulfanylidene-λ5-phosphane 
Molecular Weight: 456.538762 g/mol
Molecular Formula: C₁₂H₂₆O₆P₂S₄ 
Density: 1.33 g/cm³ 
Melting Point: -2.00E+01 deg C
Boiling Point: 504.2 °C at 760 mmHg
Flash Point: 258.7 °C
Storage Temp.: 0-6 °C
Index of Refraction: 1.553
Molar Refractivity: 109.47 cm³
Molar Volume: 341.9 cm³
Polarizability: 43.39*10^-24 cm³
Surface Tension: 54.5 dyne/cm 
Enthalpy of Vaporization: 74.43 kJ/mol 
log P (octanol-water): 3.450
Water Solubility: 1.550 mg/L 
Vapor Pressure: 8.76E-08 mm Hg 
Henry's Law Constant: 1.35E-11 atm-m³/mole 
Atmospheric OH Rate Constant: 7.94E-10 cm³/molecule-sec
XLogP3-AA: 4.3
H-Bond Acceptor: 6
Rotatable Bond Count: 12
Exact Mass: 456.008744
MonoIsotopic Mass: 456.008744
Topological Polar Surface Area: 55.4
Heavy Atom Count: 24
Complexity: 395
Canonical SMILES: CCOP(=S)(OCC)SC1C(OCCO1)SP(=S)(OCC)OCC
InChI: InChI=1S/C12H26O6P2S4/c1-5-15-19(21,
16-6-2)23-11-12(14-10-9-13-11)24-20(22,17-7-3)18-8-4/h11-12H,5-10H2,1-4H3
InChIKey: VBKKVDGJXVOLNE-UHFFFAOYSA-N
EINECS: 201-107-7
Product Categories: AcaricidesPesticides&Metabolites; Alpha sort; D; DAlphabetic; DIO - DIZPesticides; Insecticides; Organophorous; Pesticides; Pesticides&Metabolites

 Dioxathion (CAS NO.78-34-2) is used for the control of insects and mites on grapes, citrus, walnuts, ornamentals, apples, pears, and quince. It Also used as a spray or dip for the control of ticks, lice, hornfly, and sheep ked on cattle, goats, sheep, and hogs.

NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-125 ,1978. . EPA Extremely Hazardous Substances List.

Poison by ingestion, inhalation, skin contact, and intraperitoneal routes. Mutation data reported. A cholinesterase inhibitor. When heated to decomposition it emits very toxic fumes of PO_x and SO_x. See also PARATHION.
Hazard Codes: T+, N
Risk Statements: 24-26/28-50/53
R24: Toxic in contact with skin. 
R26/28: Very toxic by inhalation and if swallowed. 
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 28-36/37-45-60-61 
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S36/37: Wear suitable protective clothing and gloves. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S60: This material and its container must be disposed of as hazardous waste. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 3018
RTECS: TE3350000
HazardClass: 6.1(a)
PackingGroup: I

OSHA PEL: TWA 0.2 mg/m³ (skin)
ACGIH TLV: TLV: TWA 0.1 mg/m³ (skin); Not Classifiable as a Human Carcinogen

 Dioxathion (CAS NO.78-34-2) is also called 1,4-Diossan-2,3-diil-bis(O,O-dietil-ditiofosfato) [Italian] ; 1,4-Diossan-2,3-diyl-bis(O,O-dietil-ditiofosfato) [Italian] ; 1,4-Dioxaan-2,3-diyl-bis(O,O-diethyl-dithiofosfaat) [Dutch] ;  1,4-Dioxan-2,3-diyl O,O,O',O'-tetraethyl di(phosphorodithioate) ; 1,4-Dioxan-2,3-diyl S,S-di(O,O-diethyl phosphorodithioate) ; 2,3-Bis(diethoxyphosphinothioylthio)-1,4-dioxane ; 2,3-P-Dioxan-S,S'-bis(O,O-diaethyldithiophosphat) ; Bis(dithiophosphate de O,O-diethyle) de S,S'-(1,4-dioxanne-2,3-diyle) ; S,S'-(1,4-Dioxane-2,3-diyl) O,O,O',O'-tetraethyl bis(phosphorodithioate) ; p-Dioxane-2,3-dithiol, S,S-diester with O,O-diethyl phosphorodithioate ; p-Dioxane-2,3-diyl ethyl phosphorodithioate ; CCRIS 270 ; Caswell No. 393 ; Co-Nav ; Dioxane phosphate . Dioxathion (CAS NO.78-34-2) is dark amber viscous liquid. Dioxathion is stable in water at a neutral pH. It is stable and incompatible with strong acids, alkalies. Dioxathion is heat sensitive. Dioxathion may react with iron or tin surfaces. Dioxathion may be hydrolyzed by strong acids or alkalis. . Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. Dioxathion is very toxic. Probable oral lethal dose for humans is 50-500 mg/kg or between 1 teaspoonful and 1 oz. for a 70 kg (150 lb.) person. It is a cholinesterase inhibitor. Death is primarily due to respiratory arrest arising from failure of the respiratory center, paralysis of respiratory muscles, intense bronchoconstriction, or all three. Shock can shatter container, releasing contents. (Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated to decomposition, Dioxathion emits highly toxic fumes of oxides of nitrogen, phosphorus, and sulfur. Avoid alkali materials and heat. Dioxathion is unstable to iron or tin surfaces and when mixed with certain carriers.