7801-18-5 Usage
Uses
Used in Pharmaceutical Industry:
11alpha-hydroxyandrosta-1,4-diene-3,17-dione is used as an intermediate compound in the synthesis of various pharmaceutical products. Its role in the preparation of anti-osteoporosis active compounds is particularly noteworthy, as it contributes to the development of medications aimed at combating bone loss and improving bone health.
Additionally, due to its origin as a testosterone metabolite, 11alpha-hydroxyandrosta-1,4-diene-3,17-dione may also be utilized in the research and development of other hormone-related therapies and treatments, further expanding its applications within the pharmaceutical sector.
Check Digit Verification of cas no
The CAS Registry Mumber 7801-18-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,8,0 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 7801-18:
(6*7)+(5*8)+(4*0)+(3*1)+(2*1)+(1*8)=95
95 % 10 = 5
So 7801-18-5 is a valid CAS Registry Number.
7801-18-5Relevant academic research and scientific papers
Microbial hydroxylation of steroids. 11. Hydroxylation of A-nor-, B-homo-Δ1-, and Δ1-testosterone acetates by Rhizopus arrhizus
Holland, Herbert L.,Chenchaiah, P. Chinna
, p. 1127 - 1131 (2007/10/02)
The testosterone derivatives A-nortestosterone acetate and B-homo-Δ1-testosterone acetate have been incubated with Rhizopus arrhizus, a fungus which hydroxylates testosterone at the C-6β and C-11α positions.These modes of hydroxylation were also observed for the A-nor steroid.The B-homo steroid, however, was oxidized at C-2β and concurrently hydroxylated at C-6β and C-7aβ (but not at C-11) by R. arrhizus. Δ1 steroids of conventional skeleton were hydroxylated at C-11α by R. arrhizus; in addition, Δ1-androstenedione was epoxidized at the 1,2β position.No C-6 hydroxylation of conventional Δ1,4-3-ketosteroids was observed..
