78031-18-2 Usage
Uses
Used in Chemical Synthesis:
3-Bromothiophene-2-carboxamide is used as a synthetic intermediate for the preparation of various organic compounds. Its reactivity and functional groups make it a versatile building block in the synthesis of complex molecules.
Used in Pharmaceutical Applications:
3-Bromothiophene-2-carboxamide is used as a key component in the development of new drugs. Its unique chemical structure allows it to be incorporated into various drug candidates, potentially leading to the discovery of novel therapeutic agents.
Used in Stille Cross-Coupling:
3-Bromothiophene-2-carboxamide is used as a reactant in Stille cross-coupling reactions, a widely employed method in organic chemistry for the formation of carbon-carbon bonds. This reaction is particularly useful in the synthesis of complex organic molecules, including those with potential pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 78031-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,0,3 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 78031-18:
(7*7)+(6*8)+(5*0)+(4*3)+(3*1)+(2*1)+(1*8)=122
122 % 10 = 2
So 78031-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H4BrNOS/c6-4-2-1-3(9-4)5(7)8/h1-2H,(H2,7,8)
78031-18-2Relevant academic research and scientific papers
The Fragmentation of 5- and 3-Substituted Thiophene-2-carboxamides Under Electron Impact
Occhipinti, Salvatore,Alberghina, Gaetano,Fisichella, Salvatore,Puglisi, Orazio,Ceraulo, Leopoldo
, p. 632 - 636 (2007/10/02)
The 70 eV electron impact mass spectra of twelve 5- and 3-substituted thiophene-2-carboxamides are discussed with the aid of exact mass measurements and labelling experiments.All mass spectra exhibit pronounced molecular ions.Some isomeric 5- and 3-substituted title compounds can be differentiated by mass spectrometry.The fragmentation is influenced by a strong 'ortho-effect' which activates the NH3 elimination.In the other cases the most important fragmentation is NH2. loss, followed by CO elimination.
