85591-99-7 Usage
Uses
Used in Chemical Synthesis:
3-Bromo-4-formyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy is used as an intermediate in the synthesis of highly active spin labelling reagents. These reagents are essential tools in the study of molecular structures, dynamics, and interactions in various chemical and biological systems. The unique properties of 3-BroMo-4-forMyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy, such as its bromine atom and formyl group, contribute to the effectiveness of the spin labelling reagents it helps produce.
In the field of Chemistry:
3-Bromo-4-formyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy is used as a key component in the development of advanced spin labelling reagents. Its role in this application is crucial for enhancing the understanding of molecular behavior and facilitating the discovery of new chemical compounds and reactions. 3-BroMo-4-forMyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy's structural features make it a valuable asset in the synthesis of these specialized reagents, which have a wide range of applications in research and industry.
Check Digit Verification of cas no
The CAS Registry Mumber 85591-99-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,5,9 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 85591-99:
(7*8)+(6*5)+(5*5)+(4*9)+(3*1)+(2*9)+(1*9)=177
177 % 10 = 7
So 85591-99-7 is a valid CAS Registry Number.
85591-99-7Relevant academic research and scientific papers
A Bifunctional Spin Label for Ligand Recognition on Surfaces
Hollas, Michael A.,Webb, Simon J.,Flitsch, Sabine L.,Fielding, Alistair J.
, p. 9449 - 9453 (2017/08/01)
In situ monitoring of biomolecular recognition, especially at surfaces, still presents a significant technical challenge. Electron paramagnetic resonance (EPR) of biomolecules spin-labeled with nitroxides can offer uniquely sensitive and selective insights into these processes, but new spin-labeling strategies are needed. The synthesis and study of a bromoacrylaldehyde spin label (BASL), which features two attachment points with orthogonal reactivity is reported. The first examples of mannose and biotin ligands coupled to aqueous carboxy-functionalized gold nanoparticles through a spin label are presented. EPR spectra were obtained for the spin-labeled ligands both free in solution and attached to nanoparticles. The labels were recognized by the mannose-binding lectin, Con A, and the biotin-binding protein avidin-peroxidase. Binding gave quantifiable changes in the EPR spectra from which binding profiles could be obtained that reflect the strength of binding in each case.
