78064-94-5Relevant academic research and scientific papers
Redox-neutral α-C-H bond functionalization of secondary amines with concurrent C-P bond formation/N-alkylation
Das, Deepankar,Seidel, Daniel
supporting information, p. 4358 - 4361 (2013/09/24)
Redox-neutral formation of C-P bonds in the α-position of amines was achieved via a process that features a combination of an oxidative α-C-H bond functionalization and a reductive N-alkylation. Benzoic acid functions as an efficient catalyst in this three-component reaction of cyclic secondary amines, aldehydes and phosphine oxides to provide rapid access to α-amino phosphine oxides not easily accessible by classic Kabachnik-Fields reactions.
Tetraalkylammonium Trihydridocyanoborates. Versatile, Selective Reagents for Reductive Aminations in Nonpolar Media
Hutchins, Robert O.,Markowitz, Morris
, p. 3571 - 3574 (2007/10/02)
Tetrabutylammonium cyanoborohydride or the combination of sodium cyanoborohydride with Aliquat 336 provides useful, convenient reagents for reductive amination of aldehydes and ketones in aprotic or protic media.
