78075-70-4

Basic information

• Product Name: N-[(S)-α-methylbenzyl]-4(S)-phenylazetidin-2-one
• CAS NO: 78075-70-4
• Molecular Weight: 251.328
• Mol File: 78075-70-4.mol

Chemical Properties

• CAS DataBase Reference: N-[(S)-α-methylbenzyl]-4(S)-phenylazetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(S)-α-methylbenzyl]-4(S)-phenylazetidin-2-one(78075-70-4)
• EPA Substance Registry System: N-[(S)-α-methylbenzyl]-4(S)-phenylazetidin-2-one(78075-70-4)

Safety Data

• Hazardous Substances Data: 78075-70-4(Hazardous Substances Data)

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 100-52-7 benzaldehyde 
• 127-19-5 N,N-dimethyl acetamide 
• 3129-98-4 (S)-N-benzylidene(1-phenylethylamine) 
• 618-42-8 1-piperidin-1-yl-ethanone 

Relevant articles and documents

Solvent-free stereoselective synthesis of β-aryl-β-amino acid esters by the Rodionov reaction using microwave irradiation

A rapid method for the title synthesis of β-aryl-β-amino acid esters was developed, and the absolute configurations of newly formed C-3 chiral centres in the major and minor diastereomers of the resulting ethyl N-[(S)-α-methylbenzyl]-β-amino-β-phenyl-propionate were determined.

Diastereoface-Differentiating Synthesis of Substituted β-Lactams from Chiral Imines and/or Chiral α-Chloro Iminium Chlorides

Reaction of imines carrying a chiral substituent at a nitrogen atom with symmetric or prochiral α-chloro iminium chlorides leads in a diastereoface-differentiating reaction to a mixture of diatereoisomeric or epimeric β-lactams.Attempts were made to determine the absolute configuration of obtained chiral β-lactams.Reaction of prochiral imines with chiral α-chloro iminium chlorides also provides mixtures of diastereomeric β-lactams or their enantiomers with a clear selectivity.