78075-71-5Relevant academic research and scientific papers
Solvent-free stereoselective synthesis of β-aryl-β-amino acid esters by the Rodionov reaction using microwave irradiation
Romanova,Gravis,Kudan,Bundel'
, p. 26 - 27 (2001)
A rapid method for the title synthesis of β-aryl-β-amino acid esters was developed, and the absolute configurations of newly formed C-3 chiral centres in the major and minor diastereomers of the resulting ethyl N-[(S)-α-methylbenzyl]-β-amino-β-phenyl-propionate were determined.
Asymmetric synthesis of syn- and anti-α-deuterio-β3- phenylalanine derivatives
Davies, Stephen G.,Foster, Emma M.,McIntosh, Catherine R.,Roberts, Paul M.,Rosser, Timothy E.,Smith, Andrew D.,Thomson, James E.
experimental part, p. 1035 - 1050 (2011/10/04)
The conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl) amide to a range of aryl substituted tert-butyl cinnamate esters followed by reaction of the resultant lithium β-amino enolates with D2O provides access to anti configured α-deut
Lithium (α-Methylbenzyl)allylamide: A Differentially Protected Chiral Ammonia Equivalent for the Asymmetric Synthesis of β-Amino Acids and β-Lactams
Davies, Stephen G.,Fenwick, David R.
, p. 1109 - 1110 (2007/10/02)
The addition products from the highly stereoselective conjugate additions of lithium (αS)-(α-methylbenzyl)allylamide to α,β-unsaturated tert-butyl esters are efficiently deallylated with tris(triphenylphosphine)rhodium(I) chloride and converted, after tra
Diastereoface-Differentiating Synthesis of Substituted β-Lactams from Chiral Imines and/or Chiral α-Chloro Iminium Chlorides
Rogalska, Ewa,Belzecki, Czeslaw
, p. 1397 - 1402 (2007/10/02)
Reaction of imines carrying a chiral substituent at a nitrogen atom with symmetric or prochiral α-chloro iminium chlorides leads in a diastereoface-differentiating reaction to a mixture of diatereoisomeric or epimeric β-lactams.Attempts were made to determine the absolute configuration of obtained chiral β-lactams.Reaction of prochiral imines with chiral α-chloro iminium chlorides also provides mixtures of diastereomeric β-lactams or their enantiomers with a clear selectivity.
