78075-83-9Relevant academic research and scientific papers
Mild reduction with silanes and reductive amination of levulinic acid using a simple manganese catalyst
Garcia, Juventino J.,Roa, Diego A.
, (2020/12/17)
A manganese-based catalytic system using the commercially available complex [Mn(CO)5Br] was studied for the selective reduction of levulinic acid (LA) to 2-methyl-tetrahydrofuran (MTHF). We further studied the production of pyrrolidines via its reductive amination using silanes (phenylsilane and tetramethyldisiloxane). The results showed high efficiency and selectivity for this reaction leading to high yields using mild reaction conditions.
AZAINDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS
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Page/Page column 85, (2008/06/13)
Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject.
PHOSPHOLIPASE INHIBITORS, INCLUDING MULTI-VALENT PHOSPHOLIPASE INHIBITORS, AND USE THEREOF, INCLUDING AS LUMEN-LOCALIZED PHOSPHOLIPASE INHIBITORS
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Page/Page column 229, (2010/11/27)
The present invention provides methods and compositions for the treatment of phospholipase-related conditions. In particular, the invention provides a method of treating insulin-related, weight-related conditions and/or cholesterol-related conditions in an animal subject. The method generally involves the administration of a non-absorbed and/or effluxed phospholipase A2 inhibitor that is localized in a gastrointestinal lumen.
Multivalent indole compounds and use thereof as phospholipase-A2 inhibitors
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Page/Page column 122-123, (2010/11/27)
Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject.
REARRANGEMENT OF 1-PIPERIDINOCYCLOPROPYL KETIMINES. A SYNTHESIS OF 2-SUBSTITUTED PYRROLES
Wasserman, Harry H.,Dion, Robert P.,Fukuyama, James M.
, p. 629 - 631 (2007/10/02)
On heating 1-(N-piperidino)cyclopropyl ketimines with HBF4, rearrangement to 2-substituted pyrroles takes place.
Synthesis of N-Substituted Prodigiosenes
Brown, David,Griffiths, David,Rider, Margaret E.,Smith, Rodney C.
, p. 455 - 464 (2007/10/02)
Prodigiosenes bearing N-methyl or N-benzyl groups in each of the three pyrrole rings have been prepared by coupling either a bipyrrole with a pyrrolecarbaldehyde or a bipyrrolecarbaldehyde with an α-free pyrrole.Synthesis via the bipyrrole route can lead
