78080-70-3Relevant academic research and scientific papers
Introduction of an efficient DABCO-based bis-dicationic ionic salt catalyst for the synthesis of arylidenemalononitrile, pyran and polyhydroquinoline derivatives
Zabihzadeh, Mehdi,Omidi, Atefeh,Shirini, Farhad,Tajik, Hassan,Langarudi, Mohaddeseh Safarpoor Nikoo
, (2020/01/23)
—An affordable DABCO-based bis-dicationic ionic salt ([(DABCO)2C3H5OH]·2Cl) was utilized for the synthesis of arylidenemalononitrile, tetrahydrobenzo[b]pyran, pyrano[2,3-d]-pyrimidinone (thione), dihydropyrano[3,2-c]chrome
Dihydropyridines as potential α-amylase and α-glucosidase inhibitors: Synthesis, in vitro and in silico studies
Arfeen, Minhajul,Chigurupati, Sridevi,Hameed, Shehryar,Kanwal,Khan, Khalid Mohammed,Khan, Muhammad Naseem,Shamim, Shahbaz,Taha, Muhammad,Yousuf, Hina
, (2020/01/23)
Dihydropyridine derivatives 1–31 were synthesized via one-pot solvent free condition and screened for in vitro against α-amylase and α-glucosidase enzyme. The synthetic derivatives 1–31 showed good α-amylase inhibition in the range of IC50 = 2.
Covalently anchored sulfamic acid on cellulose as heterogeneous solid acid catalyst for the synthesis of structurally symmetrical and unsymmetrical 1,4-dihydropyridine derivatives
Karhale, Shrikrishna,Bhenki, Chandrakant,Rashinkar, Gajanan,Helavi, Vasant
supporting information, p. 5133 - 5141 (2017/07/12)
A novel heterogeneous solid acid catalyst has been prepared by covalent grafting of chlorosulphonic acid on amino-functionalized cellulose (Cell-Pr-NHSO3H). The structure of the catalyst was assessed by FT-IR, solid-state CP/MAS 13C-
Solvent-free synthesis of polyhydroquinoline derivatives employing mesoporous vanadium ion doped titania nanoparticles as a robust heterogeneous catalyst via the Hantzsch reaction
Dharma Rao,Nagakalyan,Prasad
, p. 3611 - 3616 (2017/01/24)
Mesoporous vanadium ion doped titania nanoparticles (V-TiO2) were used as a reusable and robust heterogeneous catalyst for one-pot four component synthesis of polyhydroquinoline derivatives via the esteemed Hantzsch reaction using arylaldehyde,
Protic pyridinium ionic liquid as a green and highly efficient catalyst for the synthesis of polyhydroquinoline derivatives via Hantzsch condensation in water
Tajbakhsh, Mahmood,Alinezhad, Heshmatollah,Norouzi, Mohammad,Baghery, Saeed,Akbari, Maryam
, p. 44 - 48 (2013/03/13)
The four-component Hantzsch condensation reaction of dimedone, ethyl acetoacetate, ammonium acetate and various aromatic and aliphatic aldehydes in the presence of 2-methylpyridinium trifluoromethanesulfonate ([2-MPyH]OTf) as a green and highly efficient
Cu(2) schiff base complex as a highly efficient catalyst for the synthesis of polyhydroquinoline derivatives via hantzsch condensation in water
Vahdat, Seyed Mohammad
, p. 782 - 787 (2014/03/21)
In the present study, Cu(II) Schiff-base complex is introduced as a highly efficient and green solid catalyst for the unsymmetrical Hantzsch condensation through a four-component coupling of various aldehydes, dimedone, ethyl acetoacetate and ammonium ace
Synthesis of polyhydroquinoline derivatives via a four-component Hantzsch condensation catalyzed by tin dioxide nanoparticles
Vahdat, Seyed Mohammad,Chekin, Fereshteh,Hatami, Mehdi,Khavarpour, Maryam,Baghery, Saeed,Roshan-Kouhi, Ziba
, p. 758 - 763 (2013/08/25)
Tin dioxide (SnO2) nanoparticles efficiently catalyzed unsymmetrical four-component Hantzsch condensations of various aldehydes, dimedone, ethyl acetoacetate, and ammonium acetate to form polyhydroquinoline derivatives in excellent yields. This novel method offers several advantages over the traditional method of synthesizing these compounds, including safety, mild conditions, short reaction times, high yields, and an easy workup.
Synthesis of 4-aryl-1,4,5,6,7,8-hexahydro-5-oxo-2,7,7-trimethyl-quinoline-3-carboxylates and amides
Sainani, J. B.,Shah, A. C.,Arya, V. P.
, p. 526 - 531 (2007/10/03)
In an extension of Hantzsch aryldihydropyridine synthesis, 4-aryl-1,4,5,6,7,8-hexahydro-5-oxo-2,7,7-trimethyl-quinoline-3-carboxylates (4) and 4-aryl-1,4,5,6,7,8-hexahydro-5-oxo-2,7,7-trimethyl-quinoline-3-N-substituted amides (9) have been synthesised by the condensation of 5,5-dimethylcyclohexane-1,3-dione (dimedone) with aromatic aldehydes and β-aminocrotonates and β-aminocrotonamides.Compound 4 is also obtained by the reaction of bis-dimedonyl derivative (5) with β-aminocrotonate.Reaction of arylalkylidene acetoacetate (7) with dimedone and aq. ammonia or ammonium acetate also affords 4.
