78155-73-4 Usage
General Description
Methyl 5-fluoro-1H-indazole-3-carboxylate is a chemical compound with the molecular formula C10H8FN2O2. It is a carboxylate ester of 5-fluoro-1H-indazole-3-carboxylic acid, and it is commonly used in the pharmaceutical and agrochemical industries as a building block in the synthesis of various bioactive molecules and pharmaceutical drugs. This chemical compound exhibits a wide range of biological activities, including antifungal, antibacterial, and anti-inflammatory properties, making it a valuable precursor in drug discovery and development. Additionally, its ability to modulate various biological pathways and target specific enzymes makes it a promising candidate for the treatment of various diseases, including cancer and neurological disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 78155-73-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,1,5 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 78155-73:
(7*7)+(6*8)+(5*1)+(4*5)+(3*5)+(2*7)+(1*3)=154
154 % 10 = 4
So 78155-73-4 is a valid CAS Registry Number.
78155-73-4Relevant articles and documents
ALKYNYL ALCOHOLS AND METHODS OF USE
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Page/Page column 107; 159; 224, (2015/03/13)
The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over- activation of NF-kB signaling is observed.
Synthesis of 3-indazolecarboxylic esters and amides via Pd-catalyzed carbonylation of 3-iodoindazoles
Buchstaller, Hans-Peter,Wilkinson, Kai,Burek, Kasimir,Nisar, Yasmin
, p. 3089 - 3098 (2011/10/13)
A straightforward and effective procedure for the preparation of 1H-indazole-3-carboxylic acid esters and amides was developed. A series of functionalized 3-iodoindazoles were subjected to Pd-catalyzed carbonylations in the presence of methanol or amines,
CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II
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Page/Page column 14-15, (2010/11/26)
The invention discloses compounds of formula (I) wherein: R is a carboxylic acid or a derivative thereof; R1 and R2 are independently H or alkyl, or together R1 and R2 form an alkylene group; L1 is a
