78164-32-6

Basic information

• Product Name: 4,5-bis(trifluoromethyl)phthalic acid
• Synonyms: 4,5-bis(trifluoromethyl)phthalic acid
• CAS NO: 78164-32-6
• Molecular Weight: 302.13
• Mol File: 78164-32-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4,5-bis(trifluoromethyl)phthalic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-bis(trifluoromethyl)phthalic acid(78164-32-6)
• EPA Substance Registry System: 4,5-bis(trifluoromethyl)phthalic acid(78164-32-6)

Safety Data

• Hazardous Substances Data: 78164-32-6(Hazardous Substances Data)

Upstream product

• 1620997-88-7 C₁₂H₈F₆O₄ 
• 67193-32-2 dimethyl 4,5-diiodo-1,2-benzenedicarboxylate 
• 89-32-7 Pyromellitic dianhydride 
• 89-05-4 1,2,4,5-benzenetetracarboxylic acid 
• 147915-61-5 5,6-bis(trifluoromethyl)-1,1,3,3-tetrafluoro-1,3-dihydroisobenzofuran 
• 2341-35-7 1,2-dimethyl-4,5-bis(trifluoromethyl)benzene 

Downstream Products

• 1620997-28-5 2-((2-methylpyrimidin-4-yl)carbamoyl)-4,5-bis(trifluoromethyl)benzoic acid 
• 78164-34-8 4,5-Bis-trifluoromethyl-phthalamide 
• 78164-35-9 4,5-Bis-trifluoromethyl-phthalonitrile 

Relevant articles and documents

N-SUBSTITUTED-5-SUBSTITUTED PHTHALAMIC ACIDS AS SORTILIN INHIBITORS

The present invention is directed to N-substituted-5-substituted phthalamic acids which of formula (A). The compounds are considered useful for the treatment of diseases treatment of a neurodegenerative disease, psychiatric disease, motorneuron disease, peripheral neuropathies, pain, neuroinflammation or atherosclerosis such as Alzheimer's disease and Parkinson's disease.

A re-investigation of the reactions of pyromellitic acid and its dianhydride with sulphur tetrafluoride

The fluorination of pyromellitic acid (1) with sulphur tetrafluoride or pyromellitic dianhydride (2) by means of an SF4-HF mixture gave, besides the expected 1,2,4,5-tetrakis(trifluoromethyl)benzene (3), considerable amounts of 5,6-bis(trifluoromethyl)-1,