78228-01-0Relevant academic research and scientific papers
Regioselective Reduction of Substituted Dinitroarenes Using Baker's Yeast
Davey, Claire L.,Powell, Lawson W.,Turner, Nicholas J.,Wells, Andrew
, p. 7867 - 7870 (1994)
A range of substituted dinitroaromatic compounds have been reduced using baker's yeast (Saccharamyces cerevisiae), in some cases with very high selectivity.A model is presented to account for the origin of the selectivity together with a possible mechanism for the reduction.
Palladium-Catalyzed Thiomethylation via a Three-Component Cross-Coupling Strategy
Wang, Ming,Qiao, Zongjun,Zhao, Jiaoyan,Jiang, Xuefeng
supporting information, p. 6193 - 6197 (2018/09/25)
In this report, the combination of masked inorganic sulfur and dimethyl carbonate was designed to achieve thiomethylated cross coupling of aryl chlorides. Remarkably, this powerful strategy realized thiomethylation of nucleosides bearing unprotected ribose, chloride-containing pharmaceuticals with late-stage coupling, and herbicides possessing multiple heteroatoms and steric hindrance. Moreover, this protocol is practically amenable to multigram-scale synthesis with a lower catalysis loading and a higher yield.
Methyl aryl thioether compound, and synthetic method and applications thereof
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Paragraph 0095; 0096; 0097, (2017/07/21)
The invention discloses a methyl aryl thioether compound represented by formula 2, and a synthetic method and applications thereof. According to the synthetic method, in a reaction solvent, an aryl halide or an aromatic halide, dimethyl carbonate, and potassium thioacetate are taken as reaction raw materials, reaction is carried out in the presence of metal palladium catalyst under the action of a ligand and an alkali so as to obtain the methyl aryl thioether compound. The reaction conditions of the synthetic method are mild; the raw materials are cheap and easily available; reaction operation is simple; yield is relatively high. The methyl aryl thioether compound can be used for providing skeleton structures for the synthesis of a plurality of natural products and medicines, and can be widely applied in industrialized large-scale production.
THE THIOLATE ANION AS A NUCLEOPHILE PART X. REACTIONS OF SOME NITROFLUOROAROMATICS
Leblanc, Maurice E.,Peach, Michael E.,Winter, Heather M.
, p. 233 - 248 (2007/10/02)
The reactions of various nitrofluorobenzenes, C6HxFyNO2, with sodium methanethiolate have been studied in ethylene glycol/pyridine mixture as solvent.All the fluorine atoms, but not the nitrogroups, could be substituted by the methylthio group.The reactions have also been studied with the addition of a deactivating group, either methyl or amino, on the aromatic nucleus.Some of the methylthio groups in the products were oxidized to the corresponding sulfones.The new compounds isolated have been characterized and their spectra (IR, NMR and mass) examined.
