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(3-chloro-4,5-dihydro-1,2-oxazol-5-yl)[(9H-fluoren-9-ylmethoxy)carbonyl]aminoacetic acid is a complex organic compound featuring a chlorinated oxazol ring attached to an aminoacetic acid group. It also incorporates a fluorenylmethoxy carbonyl (Fmoc) protecting group, which is widely utilized in peptide synthesis to shield the amino group. (3-chloro-4,5-dihydro-1,2-oxazol-5-yl)[(9H-fluoren-9-ylmethoxy)carbonyl]aminoacetic acid is characterized by its unique structure and functional groups, making it a promising candidate for drug development or as a key intermediate in the synthesis of pharmaceuticals. The chlorinated oxazol ring is known to contribute to biological activity, while the Fmoc group allows for selective removal to facilitate further chemical modifications. (3-chloro-4,5-dihydro-1,2-oxazol-5-yl)[(9H-fluoren-9-ylmethoxy)carbonyl]aminoacetic acid's intriguing structural features and potential applications render it a valuable asset in the field of medicinal chemistry.

78233-96-2

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78233-96-2 Usage

Uses

Used in Pharmaceutical Development:
(3-chloro-4,5-dihydro-1,2-oxazol-5-yl)[(9H-fluoren-9-ylmethoxy)carbonyl]aminoacetic acid serves as a potential drug candidate due to its unique structural composition and functional groups. The chlorinated oxazol ring endows the compound with biological activity, which can be harnessed for therapeutic purposes. The Fmoc protecting group enables selective removal and further chemical modifications, allowing for the optimization of the compound's pharmacological properties.
Used in Peptide Synthesis:
In the field of peptide synthesis, (3-chloro-4,5-dihydro-1,2-oxazol-5-yl)[(9H-fluoren-9-ylmethoxy)carbonyl]aminoacetic acid acts as a key intermediate. The Fmoc protecting group present in the compound is commonly used to protect the amino group during the synthesis process. This protection allows for the controlled addition of amino acids to the growing peptide chain, ensuring the correct sequence and preventing unwanted side reactions. The selective removal of the Fmoc group is crucial for the successful synthesis of peptides with desired properties and functions.
Used in Medicinal Chemistry Research:
(3-chloro-4,5-dihydro-1,2-oxazol-5-yl)[(9H-fluoren-9-ylmethoxy)carbonyl]aminoacetic acid is utilized in medicinal chemistry research to explore its potential applications and optimize its structure for specific therapeutic targets. (3-chloro-4,5-dihydro-1,2-oxazol-5-yl)[(9H-fluoren-9-ylmethoxy)carbonyl]aminoacetic acid's unique features and functional groups provide a foundation for the development of new drugs or the improvement of existing ones. Researchers can investigate the compound's interactions with biological targets, its pharmacokinetics, and its potential side effects, ultimately contributing to the advancement of medicinal chemistry and drug discovery.

Check Digit Verification of cas no

The CAS Registry Mumber 78233-96-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,2,3 and 3 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 78233-96:
(7*7)+(6*8)+(5*2)+(4*3)+(3*3)+(2*9)+(1*6)=152
152 % 10 = 2
So 78233-96-2 is a valid CAS Registry Number.

78233-96-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(3-chloro-4,5-dihydro-1,2-oxazol-5-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)acetic acid

1.2 Other means of identification

Product number -
Other names 5-Isoxazoleacetic acid,5-dihydro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:78233-96-2 SDS

78233-96-2Downstream Products

78233-96-2Relevant academic research and scientific papers

α(Substituted) amino-3-substituted-2-isoxazoline-5-acetic acids (esters)

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, (2008/06/13)

Chemical process for preparing AT-125 and its analogs and intermediates used in the process.

α(substituted) Amino-3-substituted-2-isoxazoline-5-acetic acids (esters)

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, (2008/06/13)

Chemical process for preparing AT-125 and its analogs and intermediates used in the process.

Substituted alkoxy carbonyl-3-oxo-α-phthalimido-5-isoxozolidineacetic acids

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, (2008/06/13)

Analogs of tricholomic acids and process for preparing them.

Method for preparing (αS,5S)-α-amino-3-chloro-2-isoxazoline-5-acetic acid (AT-125) and analogs thereof

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, (2008/06/13)

Chemical process for preparing AT-125 and its analogs and intermediates used in the process.

Purification of AT-125

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, (2008/06/13)

Process for the purification of L-(αs,5s)-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125). Also provided are AT-125 analogs prepared in the process.

Purification of AT-125

-

, (2008/06/13)

Process for the purification of L-(αS,5S)-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125). Also provided are AT-125 analogs prepared in the process.

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