782482-50-2

Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-(TERT-BUTYLAMINO)-1-(2,4-DIFLUOROPHENYL)ETHANOL is used as a chiral building block for the synthesis of various drugs. Its ability to create enantiomerically pure compounds allows for the development of pharmaceuticals with targeted pharmacological properties, enhancing their efficacy and reducing potential side effects.
Used in Agrochemical Industry:
(S)-2-(TERT-BUTYLAMINO)-1-(2,4-DIFLUOROPHENYL)ETHANOL is also utilized as an intermediate in the production of agrochemicals. Its chiral properties enable the creation of enantiomerically pure compounds with specific pesticidal or herbicidal activities, improving the effectiveness and selectivity of these chemicals in agricultural applications.

InChI:InChI=1/C12H17F2NO/c1-12(2,3)15-7-11(16)9-5-4-8(13)6-10(9)14/h4-6,11,15-16H,7H2,1-3H3/t11-/m1/s1

Upstream product

• 75-64-9 tert-butylamine 
• 330156-49-5 (S)-2-chloro-1-(2’,4’-difluorophenyl)ethanol 
• 51336-94-8 2-chloro-1-(2,4-dichlorophenyl)ethanone 

Downstream Products

• 782482-51-3 3-{tert-butyl[(2S)-2-(2,4-difluorophenyl)-2-hydroxyethyl]amino}propanenitrile 
• 852305-05-6 ethyl N-(tert-butyl)-N-[(2S)-2-(2,4-difluorophenyl)-2-hydroxyethyl]-β-alaninate 
• 794500-76-8 (3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonitrile 
• 794500-77-9 (3R,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonitrile 
• 1373237-26-3 C₁₆H₂₂F₂N₂O 

Relevant academic research and scientific papers

ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS

Certain novel N-acylated piperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention

ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS

Certain novel N-acylated piperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention

Enantioselective nitrile anion cyclization to substituted pyrrolidines. A highly efficient synthesis of (3S,4R)-N-tert-butyl-4-arylpyrrolidine-3- carboxylic acid

(Chemical Equation Presented) A practical asymmetric synthesis of N-tert-butyl disubstituted pyrrolidines via a nitrile anion cyclization strategy is described. The five-step chromatography-free synthesis of (3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrr

ACYLATED PIPERAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS

Certain novel N-acylated piperazine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention

BICYCLIC PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS

Certain novel bicyclic N-acylated piperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or p

PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYRROLIDINE CARBOXYLIC ACIDS

A novel process is provided for the preparation of pyrrolidine carboxylic acids, and the useful intermediates obtained therein. These compounds are intermediates for the synthesis of melanocortin-4 receptor (MC-4R), which are useful for the treatment of d