78267-54-6

Basic information

• Product Name: TRANS-1,1-DIACETOXY-2-BUTENE)
• Synonyms: TRANS-1,1-DIACETOXY-2-BUTENE)
• CAS NO: 78267-54-6
• Molecular Formula: C₈H₁₂O₄
• Molecular Weight: 172.17848
• Mol File: 78267-54-6.mol
• Article Data: 31

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TRANS-1,1-DIACETOXY-2-BUTENE)(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-1,1-DIACETOXY-2-BUTENE)(78267-54-6)
• EPA Substance Registry System: TRANS-1,1-DIACETOXY-2-BUTENE)(78267-54-6)

Safety Data

• Hazardous Substances Data: 78267-54-6(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 123-73-9 crotonaldehyde 
• 123-73-9 trans-Crotonaldehyde 
• 107-89-1 acetaldol 

Downstream Products

• 169689-17-2 (2E,4R)-5,5-bis(phenylsulfonyl)-4-acetoxy-2-hexene 
• 64-19-7 acetic acid 
• 123-73-9 crotonaldehyde 
• 141-78-6 ethyl acetate 
• 68020-98-4 α-cyanocrotyl acetate 
• 342906-95-0 dimethyl (2'E,1'S)-2-(4'-acetoxy-3'-buten-2'-yl)-2-benzylmalonate 
• 123-73-9 trans-Crotonaldehyde 
• 25611-05-6 C₁₂H₁₄O₂ 
• 7614-93-9 1,3-diphenyl-1-butene 
• 342909-32-4 (E,S)-3-methyl-6,6-bis(phenylsulfonyl)-4-heptenoic acid 
• 97509-92-7 C₃₀H₂₈O₈S₄ 
• 77105-05-6 Enolacetat d. β-Methyl-4-isopropyl-hydrozimtaldehyds 
• 484-11-7 2.9-dimethyl-1,10-phenanthroline 

Relevant articles and documents

Solvent-free Chemoselective Synthesis of 1,1-diacetates Catalyzed by Iron Zirconium Phosphate

In the present study, a mild, rapid, and efficient method for the protection of aldehydes with acetic anhydride (AA) in the presence of iron zirconium phosphate (ZPFe), at room temperature is reported. Selective conversion of aldehydes was observed in the presence of ketones. Under these conditions, different aldehydes bearing electron-withdrawing and electron-donating substituents were reacted with AA and the corresponding 1,1-diacetates (acylals) were obtained in high to excellent yields. The steric and electronic properties of the different substrates had a significant influence on the reaction conditions. Also, the deprotection of 1,1-diacetates has been achieved using this catalyst in water. The catalyst was characterized by several physico-chemical techniques. It was recovered easily from the reaction mixture, regenerated, and reused at least 7 times without significant loss in catalytic activity. This protocol has the advantages of easy availability, stability, reusability of the eco-friendly catalyst, chemoselectivity, simple experimental and work-up procedure, solvent-free conditions and only a stoichiometric amount of AA is needed.

Ultrasound-assisted synthesis of acylals from aldehydes using Mg(CH 3SO3)2-HOAC

An efficient method for the synthesis of acylals from different aldehydes and acetic anhydride in the presence of magnesium methanesulfonate-acetic acid under ultrasound irradiation at room temperature is achieved. Only 1.5mol% of magnesium methanesulfonate and a small quantity of acetic acid are needed to effect the reaction. Selective conversion of aldehydes is observed in the presence of ketones. The catalyst remains active and exhibits no substantial loss of activity or selectivity in up to three reaction cycles.

Chromic(III) sulfamate as a versatile catalyst for organic synthesis

Chromic sulfamate was synthesized and used as catalyst for the first time in various organic reactions such as the transformation of aldehydes or ketones and indole to bis(indolyl)methanes, the transformation of aldehydes and acetic anhydride to 1,1-diacetates and Biginelli reaction. The advantages of the chromic sulfamate are ease of preparation, easy handling, simple work-up and versatility.