78269-62-2Relevant academic research and scientific papers
First aromatic electrophilic iodination reaction on the solid-phase: Iodination of bioactive peptides
Arsequell, Gemma,Espuna, Gemma,Valencia, Gregorio,Barluenga, Jose,Carlon, Raquel Perez,Gonzalez, Jose M.
, p. 7393 - 7396 (1998)
Direct iodination of Tyr residues of peptides anchored on solid supports was accomplished, for the first time, by aromatic electrophilic attack of iodonium ions provided by the IPy2BF4 reagent. Compatibility studies of the iodination with routine solid-phase synthesis protocols are reported.
