78283-37-1

Upstream product

• 490-79-9 2,5-dihydroxybenzoic acid. 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 1355333-49-1 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 2,5-dihydroxybenzoate 
• 1355333-58-2 2-(3,4-dibenzyloxyphenyl)-7-benzyloxy-5-hydroxy-4-oxo-4H-chromen-3-yl 2,5-dibenzyloxybenzoate 
• 79755-47-8 2,5-bisbenzyloxyphenylacetic acid 
• 79755-48-9 1-(2,5-bisbenzyloxyphenyl)propan-2-one 
• 79755-55-8 1-(3,5-bisbenzyloxyphenyl)-2-chloropropane 
• 79755-56-9 1-(3,5-dihydroxyphenyl)-2-chloropropane 
• 79755-57-0 1-(3,5-dihydroxyphenyl)prop-1-ene 
• 34701-77-4 1-(2,5-dihydroxyphenyl)propan-2-one 
• 78311-08-7 5,8-dibenzyloxy-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline 
• 79357-92-9 5,8-dihydroxy-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride 
• 78283-42-8 N-(2,5-dibenzyloxyphenethyl)-2-(3,4,5-trimethoxyphenyl)acetamide 
• 78283-40-6 2,5-bisbenzyloxybenzyl cyanide 
• 78283-39-3 2,5-bisbenzyloxybenzyl chloride 
• 705282-04-8 N-{4-[3-(2,5-bis-benzyloxy-benzoylamino)-propylamino]-butyl}-2-({4-[3-(2,5-bis-benzyloxy-benzoylamino)-propylamino]-butylcarbamoyl}-methyl)-2-hydroxy-succinamic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis and antiviral activity of substituted quercetins

Influenza viruses are important pathogens that cause respiratory infections in humans and animals. In addition to vaccination, antiviral drugs against influenza virus play a significant role in controlling viral infections by reducing disease progression and virus transmission. Plant derived polyphenols are associated with antioxidant activity, anti-carcinogenic, and cardio- and neuro-protective actions. Some polyphenols, such as resveratrol and epigallocatechin gallate (EGCG), showed significant anti-influenza activity in vitro and/or in vivo. Recently we showed that quercetin and isoquercetin (quercetin-3-β-d-glucoside), a glucoside form of quercetin, significantly reduced the replication of influenza viruses in vitro and in vivo (isoquercetin). The antiviral effects of isoquercetin were greater than that of quercetin with lower IC50 values and higher in vitro therapeutic index. Thus, we investigated the synthesis and antiviral activities of various quercetin derivatives with substitution of C3, C3′, and C5 hydroxyl functions with various phenolic ester, alkoxy, and aminoalkoxy moieties. Among newly synthesized compounds, quercetin-3-gallate which is structurally related to EGCG showed comparable antiviral activity against influenza virus (porcine H1N1 strain) to that of EGCG with improved in vitro therapeutic index.

Total Synthesis of Petrobactin and Its Homologues as Potential Growth Stimuli for Marinobacter hydrocarbonoclasticus, an Oil-Degrading Bacteria

A modular synthesis was developed to access petrobactin, a catechol-containing siderophore isolated from Marinobacter hydrocarbonoclasticus. A range of petrobactin homologues with differing dihydroxybenzamide motifs and in one case an increased number of

Biosynthesis of Fungal Metabolites. Terrein, a Metabolite of Aspergillus terreus Thom

Terrein, a metabolite of Aspergillus terreus Thom, is biosynthesised from 3,4-dihydro-6,8-dihydroxy-3-methylisocoumarin by contraction of an aryl ring.The direction of the ring contraction has been investigated using acetate as precursor.